16532-79-9 Usage
Description
4-Bromophenylacetonitrile is an organic compound with the chemical formula C8H6BrN. It is a colorless to pale brown crystalline mass that is used as a chemical model and in the synthesis of various materials.
Uses
Used in Pharmaceutical Research:
4-Bromophenylacetonitrile is used as a chemical model for the study and analysis of human buccal absorption of pharmaceuticals. This application helps researchers understand the absorption process and develop more effective drug delivery systems.
Used in Polymer Synthesis:
In the field of polymer chemistry, 4-Bromophenylacetonitrile is used in the synthesis of new fluorene-based alternating polymers and light-emitting copolymers, such as poly(N 4,N 4-bis-(4-phenyl)-N 4,N 4′-bis-[4-(2-ethylhexyloxy)phenyl]-biphenyl-4,4′-diamine-co-1,2-bis(4′-phenyl)-1-(9′′,9′′-dihexyl-3-fluorenyl)ethane). These materials have potential applications in the development of organic light-emitting diode (OLED) technology.
Used in OLED Material Synthesis:
4-Bromophenylacetonitrile is also used in the synthesis of N-methyl-3,4-bis(4-(N-(1-naphthyl)phenylamino)phenyl)maleimide, a novel non-doped red organic light-emitting diode (OLED) material. This material contributes to the advancement of OLED technology and its applications in display and lighting industries.
Safety Profile
Poison by intravenous
route. See also BROMIDES and NITRILES. When heated to decomposition
it emits very toxic fumes of Br-, NOx, and
CN-.
Check Digit Verification of cas no
The CAS Registry Mumber 16532-79-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,5,3 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16532-79:
(7*1)+(6*6)+(5*5)+(4*3)+(3*2)+(2*7)+(1*9)=109
109 % 10 = 9
So 16532-79-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H6BrN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5H2
16532-79-9Relevant articles and documents
-
Griffin,R.W. et al.
, p. 2109 - 2116 (1964)
-
Rapid and Simple Access to α-(Hetero)arylacetonitriles from Gem-Difluoroalkenes
Hu, Dandan,Liu, Jiayue,Ren, Hongjun,Song, Jinyu,Zhang, Jun-Qi,Zhu, Guorong
supporting information, p. 786 - 790 (2022/01/28)
A scalable cyanation of gem-difluoroalkenes to (hetero)arylacetonitrile derivatives was developed. This strategy features mild reaction conditions, excellent yields, wide substrate scope, and broad functional group tolerance. Significantly, in this reacti
Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst
Kim, Kunsoon,Lee, Seulchan,Hong, Soon Hyeok
supporting information, p. 5501 - 5505 (2021/07/26)
A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.
