1059705-55-3

Basic information

• Product Name: tert-butyl N-benzyl-N-(5-chloro-2-nitrophenyl)carbamate
• Synonyms: tert-butyl N-benzyl-N-(5-chloro-2-nitrophenyl)carbamate
• CAS NO: 1059705-55-3
• Molecular Weight: 362.813
• Mol File: 1059705-55-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl N-benzyl-N-(5-chloro-2-nitrophenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl N-benzyl-N-(5-chloro-2-nitrophenyl)carbamate(1059705-55-3)
• EPA Substance Registry System: tert-butyl N-benzyl-N-(5-chloro-2-nitrophenyl)carbamate(1059705-55-3)

Safety Data

• Hazardous Substances Data: 1059705-55-3(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 1635-61-6 5-chloro-2-nitroaniline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 10066-19-0 N-benzyl-N-(2-nitro-5-chlorophenyl)-amine 
• 63860-31-1 2-bromo-4-chloro-1-nitrobenzene 
• 42116-44-9 N-tert-butoxycarbonylbenzylamine 

Relevant articles and documents

Rational design of 5-HT6R ligands using a bioisosteric strategy: Synthesis, biological evaluation and molecular modelling

A bioisosteric strategy was successfully implemented with a screening protocol for new, potent 5-HT6R ligands. Initially, 2-[5-(4-methylpiperazin-1-yl)-2-nitrophenyl]-1,2,3,4-tetrahydroisoquinoline (9) was found in commercial databases using a

SUBSTITUTED PHENYL-PIPERAZINE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS

The present invention relates to substituted phenyl-piperazine compounds of general formula (I), a process for their preparation, medicaments comprising said substituted phenyl-piperazine compounds as well as the use of said substituted phenyl-piperazine compounds for the preparation of medicaments, which are particularly suitable for the prophylaxis and/or treatment of disorders or diseases that are at least partially mediated via 5-HT6 receptors.