10600-83-6

Basic information

• Product Name: 2,5-BIS(4-HYDROXYPHENYL)-1,3,4-OXADIAZOLE
• Synonyms: 2,5-BIS(4-HYDROXYPHENYL)-1,3,4-OXADIAZOLE;4-[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenol;Phenol, 4,4'-(1,3,4-oxadiazole-2,5-diyl)bis-
• CAS NO: 10600-83-6
• Molecular Formula: C₁₄H₁₀N₂O₃
• Molecular Weight: 254.24
• Product Categories: pharmacetical
• Mol File: 10600-83-6.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 501.2°Cat760mmHg
• Flash Point: 256.9°C
• Appearance: /
• Density: 1.366g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.648
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,5-BIS(4-HYDROXYPHENYL)-1,3,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-BIS(4-HYDROXYPHENYL)-1,3,4-OXADIAZOLE(10600-83-6)
• EPA Substance Registry System: 2,5-BIS(4-HYDROXYPHENYL)-1,3,4-OXADIAZOLE(10600-83-6)

Safety Data

• Hazardous Substances Data: 10600-83-6(Hazardous Substances Data)

Usage

General Description

2,5-BIS(4-HYDROXYPHENYL)-1,3,4-OXADIAZOLE, also known as bisphenol O, is a chemical compound used in the production of a wide range of products, including plastics, adhesives, and thermal paper. It is derived from bisphenol A, a widely used industrial chemical. Bisphenol O is known for its high thermal stability, which makes it suitable for use in materials that require resistance to high temperatures. However, there is growing concern about its potential health effects, as it has been found to be an endocrine disruptor and has been linked to various health issues, including reproductive and developmental problems. Due to these concerns, efforts are being made to find alternative materials and chemicals to replace bisphenol O in various industrial applications.

InChI:InChI=1/C14H10N2O3/c17-11-5-1-9(2-6-11)13-15-16-14(19-13)10-3-7-12(18)8-4-10/h1-8,17-18H

Upstream product

• 17696-62-7 Phenyl 4-hydroxybenzoate 
• 5351-23-5 4-hydroxybenzoic acid hydrazide 
• 99-96-7 4-hydroxy-benzoic acid 
• 41097-49-8 p-hydroxybenzaldehyde azine 
• 847-39-2 2,5-bis(4-methoxyphenyl)-1,3,4-oxadiazole 
• 100872-56-8 4-hydroxy-[(4-hydroxyphenyl)methylidene]benzohydrazide 
• 123-08-0 4-hydroxy-benzaldehyde 
• 100-09-4 4-methoxybenzoic acid 
• 43100-26-1 N,N'-bis(p-hydroxybenzoyl)hydrazine 
• 94-30-4 ethyl 4-methoxybenzoate 
• 100-07-2 4-methoxy-benzoyl chloride 
• 3290-99-1 4-methoxybenzoic acid hydrazide 

Downstream Products

• 1000402-00-5 2-(4-undecyloxyphenyl)-5-(4-hydroxyphenyl)-[1,3,4]-oxadiazole 
• 1000402-03-8 2-[4-(4-undecyloxyphenylcarbonyloxy)phenyl]-5-(4-hydroxyphenyl)-[1,3,4]-oxadiazole 
• 1219463-66-7 2,5-bis-(4-undecyloxyphenylcarbonyloxyphenyl)[1,3,4]oxadiazole 
• 1219463-59-8 2,5-bis-{4-[4-octyloxy2-(pent-4-enyloxy)phenylcarbonyloxy]phenyl}[1,3,4]oxadiazole 
• 1154855-14-7 OC₄-2MePh(ODBP) 
• 1154855-25-0 OC₁₂-2MePh(ODBP) 
• 1154855-41-0 OC₁₂-3MePh(ODBP) 
• 1154855-33-0 2,5-bis-(4-(4-butoxy-3-methylbenzoyloxy)-phenyl)-1,3,4-oxadiazole 

Relevant articles and documents

Synthesis of 1,3,4-oxadiazole and xanthen-2-one luminophoric epoxide monomers

Epoxide derivatives of 2,5-bis-oxyphenyl-1,3,4-oxadiazoles and fluorescein, which are luminescent epoxide monomers, are synthesized. Their luminescence properties are studied. 1999 KluwerAcademic/Plenum Publishers.

Rapid synthesis of 2,5-disubstituted 1,3,4-oxadiazoles under microwave irradiation

A number of symmetrically 2,5-disubstituted 1,3,4-oxadiazoles are quickly prepared by the reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid and phosphorus pentoxide under microwave irradiation.

Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles using dry media

-

The effects of asymmetric bent-shaped compounds on the temperature range and electro-optical performances of liquid crystalline blue phases

A series of asymmetric and symmetric bent-shaped molecules with branched terminals were synthesized and characterized. Their effects on inducing blue phase and electro-optical performances were compared and analyzed experimentally. It was found that the asymmetric and symmetric compounds almost have the same effect on inducing and stabilizing blue phase, but the electro-optical performance of mixtures doped with asymmetric compounds are much better than that of mixtures doped with symmetric compounds for they have a totally different dielectric anisotropy which can contribute to a larger Kerr constant.

Electrochemical oxidation of aldehyde-N-arylhydrazones into symmetrical-2,5-disubstituted-1,3,4-oxadiazoles

A convenient, efficient and one-pot synthesis of chemically and pharmaceutically interesting symmetrical-2,5-disubstituted-1,3,4-oxadiazoles is reported. The protocol involves anodic oxidation of aldehyde-N-arylhydrazones in anhyd. MeCN-LiClO4. Constant potential electrolysis carried out in an undivided cell and platinum electrodes leads to the formation of the corresponding oxadiazoles under ambient condition and the mechanism was deduced from voltammetry studies. The reaction proceeded smoothly with high atom economy. Springer Science+Business Media Dordrecht 2013.