1060816-27-4

Basic information

• Product Name: 2-chloro-5-(4-fluorophenyl)oxazole
• Synonyms: 2-chloro-5-(4-fluorophenyl)oxazole
• CAS NO: 1060816-27-4
• Molecular Weight: 197.596
• Mol File: 1060816-27-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 307.3±34.0 °C(Predicted)
• Density: 1.345±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-chloro-5-(4-fluorophenyl)oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-5-(4-fluorophenyl)oxazole(1060816-27-4)
• EPA Substance Registry System: 2-chloro-5-(4-fluorophenyl)oxazole(1060816-27-4)

Safety Data

• Hazardous Substances Data: 1060816-27-4(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 128101-19-9 5-(4-fluorophenyl)-1,3-oxazole 

Downstream Products

• 1092465-22-9 4-[5-(4-fluoro-phenyl)-oxazol-2-ylamino]-piperidine-1-carboxylic acid tert-butyl ester 
• 21718-02-5 5-(4-fluorophenyl)oxazol-2-amine 

Relevant articles and documents

HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) wherein R1 R2, R4 and X1 are defeined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES

The present invention relates to 3,8-diaza-bicyclo[4.2.0]oct-8-yl amide derivatives of formula (I) Formula (I) wherein the relative configuration of the diazabicyclooctane moiety is cis; and wherein Ar1, and Ar 2 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.