1062626-08-7

Basic information

• Product Name: (1R,3R)-cyclohexane-1,3-diol
• Synonyms: (1R,3R)-cyclohexane-1,3-diol
• CAS NO: 1062626-08-7
• Molecular Weight: 116.16
• Mol File: 1062626-08-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (1R,3R)-cyclohexane-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R)-cyclohexane-1,3-diol(1062626-08-7)
• EPA Substance Registry System: (1R,3R)-cyclohexane-1,3-diol(1062626-08-7)

Safety Data

• Hazardous Substances Data: 1062626-08-7(Hazardous Substances Data)

Upstream product

• 504-01-8 cyclohexane-1,3-diol 
• 5515-64-0 trans-1,3-cyclohexanediol 

Relevant articles and documents

SYNTHESIS AND APPLICATION OF CHIRAL SUBSTITUTED POLYVINYLPYRROLIDINONES

Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.

Synthesis of cyclic 1,3-diols as scaffolds for spatially directed libraries

A useful design element in small molecule libraries is spatial diversity, in which binding moieties are systematically directed toward different regions of three-dimensional space. One way of achieving this is through the use of conformationally diverse scaffolds onto which various binding moieties can be placed. Such scaffolds can represent synthetic challenges of their own. In this paper, we describe a new route to chiral, cyclic 1,3-diol building blocks that features silylated dithianes as relay linchpins. These diols are subsequently used for the construction of a 24-compound pilot library bearing two amino acid residues.

Kinetic resolution of chiral auxiliaries with C2-symmetry by lipase-catalyzed alcoholysis and aminolysis

Three cyclic diols, 1,2-cyclohexanediol (1), 1,3-cyclohexanediol (2), and 1,3-cyclopentanediol (3), two acyclic unsaturated diols, 1,5-hexadiene-3,4-diol (4) and 1,7-octadiyne-3,6-diol (5), and a cyclic diamine, 1,2-cyclohexanediamine (6), have been kinetically resolved in alcoholysis and aminolysis reactions, catalyzed by Candida antarctica component B lipase, using S-ethyl thiooctanoate or ethyl octanoate as acyl donors. Acceptable stereoselectivity was achieved in most cases. Acta Chemica Scandinavica 1996.