106561-29-9

Basic information

• Product Name: Furo[2,3-d]pyrimidin-4(1H)-one, 5,6-diphenyl-
• CAS NO: 106561-29-9
• Molecular Formula: C18H12N2O2
• Molecular Weight: 288.305
• Mol File: 106561-29-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Furo[2,3-d]pyrimidin-4(1H)-one, 5,6-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[2,3-d]pyrimidin-4(1H)-one, 5,6-diphenyl-(106561-29-9)
• EPA Substance Registry System: Furo[2,3-d]pyrimidin-4(1H)-one, 5,6-diphenyl-(106561-29-9)

Safety Data

• Hazardous Substances Data: 106561-29-9(Hazardous Substances Data)

Usage

General Description

Furo[2,3-d]pyrimidin-4(1H)-one, 5,6-diphenyl- is a chemical compound with the molecular formula C21H13N3O. It belongs to the class of pyrimidine compounds and contains a fused furan and pyrimidine ring system. The compound is characterized by its diphenyl substituents at the 5 and 6 positions of the pyrimidine ring. This chemical may have potential applications in pharmaceutical and medicinal chemistry due to its unique structure and potential biological activities. Further research and study may reveal its specific properties and potential uses in various fields.

Upstream product

• 5503-73-1 2-amino-3-cyano-4,5-diphenylfuran 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 108-24-7 acetic anhydride 
• 64-18-6 formic acid 
• 1484-49-7 ethyl 2-amino-4,5-diphenyl-furan-3-carboxylate 
• 77287-34-4 formamide 
• 107833-28-3 N-(3-cyano-4,5-diphenylfuran-2-yl)formamide 

Downstream Products

• 873306-32-2 4-bromo-5,6-diphenyl-furo[2,3-d]pyrimidine 
• 65148-07-4 4-chloro-5,6-diphenylfuro[2,3-d]pyrimidine 

Relevant articles and documents

METHODS FOR THE TREATMENT OF DISORDERS RELATED TO PHOSPHORYLATION OF HISTONES

Methods for disease diagnosis, prognosis and therapy selection. Compositions for use in these methods and selected therapies for treatment are also disclosed.

Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor

Herein we reveal a simple method for the identification of novel Aurora kinase A inhibitors through substructure searching of an in-house compound library to select compounds for testing. A hydrazone fragment conferring Aurora kinase activity and heterocy

Synthesis, characterization and antimicrobial evaluation of some arylidenehy drazon of uropyrimidines and thienopyrimidines

Cyclization of hetcroaromatic o-aminoestcr with formamide afforded furo[2, 3-d]pyrimidin-4(3II)-one which was then chlorinated with thionyl chloride followed by displacement by hydrazine hydrate to furnish hydrazinofuro [2, 3-d]pyrimidine. Reaction of hydrazino derivative with formic acid gave furo[3, 2-c][ 1, 2, 4]triazolo[4, 3-c]pyrimidine. Treatment of hydrazino derivative with aromatic aldehydes afforded arylidenehydrazonofuro[2, 3-d]pyrimidine derivatives. Reaction of o-aminonitrile with carbon disulphide, followed by methylation with methyl iodide and subsequent reaction with hydrazine hydrate afforded hydrazinothieno[2, 3-d]pyrimidine. 14 derivatives were synthesized. Some of these derivatives exhibited pronounced antimicrobial activities against S. typhi, S. aureus, S. dysenteriae, V. cholerae, C. lunata, A. alternata, C. corchori, F. equeseti and M. phaseolina.