107833-28-3

Basic information

• Product Name: N-(3-cyano-4,5-diphenylfuran-2-yl)formamide
• Synonyms: N-(3-cyano-4,5-diphenylfuran-2-yl)formamide
• CAS NO: 107833-28-3
• Molecular Weight: 288.305
• Mol File: 107833-28-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(3-cyano-4,5-diphenylfuran-2-yl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-cyano-4,5-diphenylfuran-2-yl)formamide(107833-28-3)
• EPA Substance Registry System: N-(3-cyano-4,5-diphenylfuran-2-yl)formamide(107833-28-3)

Safety Data

• Hazardous Substances Data: 107833-28-3(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 5503-73-1 2-amino-3-cyano-4,5-diphenylfuran 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 2258-42-6 formyl acetic anhydride 

Downstream Products

• 873305-35-2 5,6-diphenyl-4-[(S)-(tetrahydrofuran-2-yl)-methyl]aminofuro[2,3-d]pyrimidine 
• 65148-07-4 4-chloro-5,6-diphenylfuro[2,3-d]pyrimidine 
• 106561-29-9 5,6-diphenyl-3H-furo[2,3-d]pyrimidin-4-one 

Relevant articles and documents

Structure-based design of novel Chk1 inhibitors: Insights into hydrogen bonding and protein-ligand affinity

We report the discovery, synthesis, and crystallographic binding mode of novel furanopyrimidine and pyrrolopyrimidine inhibitors of the Chk1 kinase, an oncology target. These inhibitors are synthetically tractable and inhibit Chk1 by competing for its ATP

METHODS FOR THE TREATMENT OF DISORDERS RELATED TO PHOSPHORYLATION OF HISTONES

Methods for disease diagnosis, prognosis and therapy selection. Compositions for use in these methods and selected therapies for treatment are also disclosed.