106660-11-1

Basic information

• Product Name: 3 4-DIHYDRO-3-OXO-2H-(1 4)-BENZOXAZIN-2&
• Synonyms: 3 4-DIHYDRO-3-OXO-2H-(1 4)-BENZOXAZIN-2&;(3-Oxo-3,4-dihydro-2H-benzo[1,4]oxazin-2-yl)-acetic acid;3,4-Dihydro-3-oxo-2H-1,4-benzoxazine-2-acetic acid;2-(3-keto-4H-1,4-benzoxazin-2-yl)acetic acid;2-(3-oxo-4H-1,4-benzoxazin-2-yl)acetic acid;2-(3-oxo-4H-1,4-benzoxazin-2-yl)ethanoic acid;2H-1,4-Benzoxazine-2-aceticacid, 3,4-dihydro-3-oxo-
• CAS NO: 106660-11-1
• Molecular Formula: C₁₀H₉NO₄
• Molecular Weight: 207.184
• Product Categories: API intermediates;Benzoxazines;Building Blocks;Heterocyclic Building Blocks
• Mol File: 106660-11-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 177-181 °C(lit.)
• Boiling Point: 497.3°Cat760mmHg
• Flash Point: 254.5°C
• Appearance: /
• Density: 1.362
• Vapor Pressure: 1.04E-10mmHg at 25°C
• CAS DataBase Reference: 3 4-DIHYDRO-3-OXO-2H-(1 4)-BENZOXAZIN-2&(CAS DataBase Reference)
• NIST Chemistry Reference: 3 4-DIHYDRO-3-OXO-2H-(1 4)-BENZOXAZIN-2&(106660-11-1)
• EPA Substance Registry System: 3 4-DIHYDRO-3-OXO-2H-(1 4)-BENZOXAZIN-2&(106660-11-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43
• Safety Statements: 36/37/39
• WGK Germany: 2
• HazardClass: IRRITANT
• Hazardous Substances Data: 106660-11-1(Hazardous Substances Data)

Usage

General Description

3 4-DIHYDRO-3-OXO-2H-(1 4)-BENZOXAZIN-2& is a chemical compound with the molecular formula C14H11NO3. It is a benzoxazinoid, a class of natural products found in various plant species, including maize and wheat. 3 4-DIHYDRO-3-OXO-2H-(1 4)-BENZOXAZIN-2& is known for its potential pesticidal and allelopathic properties, meaning it may have the ability to control pests and inhibit the growth of competing plant species. Its structure contains a benzoxazine ring with a carbonyl group, giving it unique chemical properties and potential bioactivity. Research on this compound and other benzoxazinoids is ongoing, as scientists continue to explore their potential applications in agriculture and medicine.

InChI:InChI=1/C10H9NO4/c12-9(13)5-8-10(14)11-6-3-1-2-4-7(6)15-8/h1-4,8H,5H2,(H,11,14)(H,12,13)/p-1/t8-/m1/s1

Upstream product

• 108-31-6 maleic anhydride 
• 95-55-6 2-amino-phenol 
• 67-56-1 methanol 
• 59256-46-1 (2Z)-4-[(2-hydroxyphenyl)amino]-4-oxobut-2-enoic acid 
• 77434-73-2 ethyl (3'-oxo-3',4'-dihydro-2'H-1',4'-benzoxazin-2'-yl)acetate 
• 106201-15-4 (E)-3-(2-Hydroxy-phenylcarbamoyl)-acrylic acid ethyl ester 
• 83549-07-9 4-((2-hydroxyphenyl) amino)-4-oxobut-2-enoic acid 
• 1400984-80-6 N-((R)-1-(3-methoxyphenyl)ethyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide 
• 22244-22-0 ethyl 3,4-dihydro-2H-benzo [b][1,4]oxazine-2-carboxylate 

Downstream Products

• 1401075-95-3 (1R)-1-(naphthalen-1-yl)-N-(2-(4-(3-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethyl)ethanamine monohydrochloride 
• 1401161-61-2 (1R)-1-(naphthalen-1-yl)-N-(2-(4-(3-(trifluoromethyl)phenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethyl)ethanamine 

Relevant articles and documents

SUBSTITUTED 3,4-DIHYDRO-2H-BENZO[B] [1,4]OXAZINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS

The present invention provides calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with t

Synthesis and antimicrobial activity of some novel 2,6,7-trisubstituted-2H-3,4-dihydro-1,4-benzoxazin-3-one derivatives

The synthesis of a new series of 2H-3,4-dihydro-1,4-benzoxazin-3-one derivatives 1-8 is accomplished in order to determine their antimicrobial activities and study their structure-activity relationships (SAR). The synthesized compounds have been tested in

The Synthesis of (3'-Oxo-3',4'-dihydro-2'H-1',4'-benzothiazin-2'-yl)acetic Acid and (3'-Oxo-3',4'-dihydro-2'H-1',4'-benzoxazin-2'-yl)acetic Acid Derivatives

Reaction of o-aminophenol with various maleic anhydrides gave first 2-hydroxymaleanilic acids (4-(2'-hydroxyphenylamino)-4-oxobut-2-enoic acids) (1), which were then converted into the 3-oxo-1,4-benzoxazines (1d-h) and (3f-l) under mild basic conditions: