1067241-20-6

Basic information

• Product Name: 1,3,2',6',2''',6''-hexa-N-(tert-butoxycarbonyl)-5''-O-(p-methylbenzenesulfonyl)-neomycin
• Synonyms: 1,3,2',6',2''',6''-hexa-N-(tert-butoxycarbonyl)-5''-O-(p-methylbenzenesulfonyl)-neomycin
• CAS NO: 1067241-20-6
• Molecular Weight: 1369.54
• Mol File: 1067241-20-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3,2',6',2''',6''-hexa-N-(tert-butoxycarbonyl)-5''-O-(p-methylbenzenesulfonyl)-neomycin(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,2',6',2''',6''-hexa-N-(tert-butoxycarbonyl)-5''-O-(p-methylbenzenesulfonyl)-neomycin(1067241-20-6)
• EPA Substance Registry System: 1,3,2',6',2''',6''-hexa-N-(tert-butoxycarbonyl)-5''-O-(p-methylbenzenesulfonyl)-neomycin(1067241-20-6)

Safety Data

• Hazardous Substances Data: 1067241-20-6(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 241820-92-8 hexa-N-Boc neomycin B 

Downstream Products

• 849676-07-9 5″-azide-1,3,2′,6′,2′″,6′″-hexa-N-(tert-butoxycarbonyl)-5″-deoxy-neomycin B 

Relevant articles and documents

Aminoglycoside-based novel probes for bacterial diagnostic and therapeutic applications

Specific detection of pathogens has long been recognized as a vital strategy in the control of infectious diseases. Two novel theranostic neomycin analogs exhibit efficient targeting, labelling and killing of broad spectrum bacteria while not damaging macrophage-like cells. Furthermore, lipidated probe 2 clearly showed antibacterial activity against methicillin-resistant S. aureus.

Design, synthesis, and antibacterial activities of neomycin-lipid conjugates: Polycationic lipids with potent gram-positive activity

Aminoglycoside antibiotics and cationic detergents constitute two classes of clinically important drugs and antiseptics. Their bacteriological and clinical efficacy, however, has decreased recently due to antibiotic resistance. We have synthesized aminogl