106731-04-8

Basic information

• Product Name: 1-chloro-2-(4-methylbenzyl)benzene
• CAS NO: 106731-04-8
• Molecular Weight: 216.71
• Mol File: 106731-04-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-chloro-2-(4-methylbenzyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-(4-methylbenzyl)benzene(106731-04-8)
• EPA Substance Registry System: 1-chloro-2-(4-methylbenzyl)benzene(106731-04-8)

Safety Data

• Hazardous Substances Data: 106731-04-8(Hazardous Substances Data)

Upstream product

• 98-51-1 4-tert-butyltoluene 
• 611-19-8 1-chloro-2-(chloromethyl)benzene 
• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 98-80-6 phenylboronic acid 
• 589-18-4 4-Methylbenzyl alcohol 
• 694-80-4 2-bromo-1-chlorobenzene 
• 78358-10-8 4-methylbenzyl mesylate 
• 22184-24-3 o-chlorobenzyl acetate 
• 108-88-3 toluene 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 1192263-63-0 C₁₅H₂₃ClO 

Relevant articles and documents

Cobalt-Catalyzed Formation of Functionalized Diarylmethanes from Benzylmesylates and Aryl Halides

A simple cobalt-catalyzed reductive coupling protocol allowing the synthesis of functionalized diarylmethanes from benzyl mesylate is described. The possibility to directly use the benzyl alcohol as a result of a two-step reaction is also presented. This method tolerates a variety of functional groups. A benzyl radical is likely involved. (Figure presented.).

Benzylation of arenes with benzyl ethers promoted by the in situ prepared superacid BF3-H2O

An efficient and environmentally friendly benzylation of arenes with benzyl ethers as benzyl donors using BF3-Et2O to generate in situ the superacid BF3-H2O as an efficient promotor has been described. A wide variety of functional groups have been investigated and found to be compatible to give the desired diarylmethanes in yields of up to 99%. The crucial role of the moisture content in this transformation has been demonstrated by detailed investigations. This journal is the Partner Organisations 2014.

ARYLALKYLATION OF 4-tert-BUTYLTOLUENE WITH SUBSTITUTED BENZYL CHLORIDES

The reaction of 4-alkylbenzyl chlorides with 4-tert-butyltoluene in the presence of titanium tetrachloride and ferric chloride leads to the formation of 2-methyl-4'-alkyl-5-tert-butyldiphenylmethanes.The arylalkylation of 4-tert-butyltoluene with 2- and 4-chlorobenzyl chlorides, catalyzed by titanium tetrachloride, leads to the formation of mixtures of 2-methyl-5-tert-butyldiphenylmethane, 2-tert-butyl-5-methyldiphenylmethane, and isomeric methyldiphenylmethanes containing a chloride atom in the benzyl fragment.The products of the reaction catalyzed by ferric chloride do not contain 2-tert-butyl-5-methylchlorodiphenylmethanes.The reacti on of 4-nitrobenzyl chloride with 4-tert-butyltoluene in the presence of ferric chloride leads to the formation of a mixture of 2-methyl-4'-nitro-5-tert-butyldiphenylmethane and isomeric methylnitrodiphenylmethanes.Under the influence of AlCl3-CH3NO2 in benzene 2,4'-dimethyl-5-tert-butyldiphenylmethane eliminates both the 4-methylbenzyl group and the tert-butyl group.Under analogous conditions 2-methyl-5-tert-butyldiphenylmethanes containing a chlorine atom or a nitro group in the benzyl fragment are dealkylated with the elimination of only the tert-butyl group.