22184-24-3

Basic information

• Product Name: 2-chlorobenzyl acetate
• CAS NO: 22184-24-3
• Molecular Formula: C₉H₉ClO₂
• Molecular Weight: 184.6196
• Mol File: 22184-24-3.mol
• Article Data: 51

Chemical Properties

• Boiling Point: 237.2°C at 760 mmHg
• Flash Point: 106.5°C
• Density: 1.197g/cm³
• Vapor Pressure: 0.0455mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: 2-chlorobenzyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chlorobenzyl acetate(22184-24-3)
• EPA Substance Registry System: 2-chlorobenzyl acetate(22184-24-3)

Safety Data

• Hazardous Substances Data: 22184-24-3(Hazardous Substances Data)

Upstream product

• 95-49-8 2-methylchlorobenzene 
• 64-19-7 acetic acid 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 89-98-5 2-chloro-benzaldehyde 
• 141-78-6 ethyl acetate 
• 150480-30-1 2-chlorobenzyl trimethylsilyl ether 
• 1058649-16-3 2-chloro-1-[(ethoxymethoxy)methyl]benzene 
• 1058649-12-9 2-chloro-1-(methoxymethoxy)methyl benzene 
• 108-05-4 vinyl acetate 
• 127-09-3 sodium acetate 
• 611-19-8 1-chloro-2-(chloromethyl)benzene 
• 64-17-5 ethanol 

Downstream Products

• 17849-38-6 2-Chlorobenzyl alcohol 
• 29921-41-3 (o-benzyl)chlorobenzene 
• 860376-18-7 1-chloro-2-(3-methylbenzyl)benzene 
• 106731-04-8 1-chloro-2-(4-methylbenzyl)benzene 
• 106731-03-7 1-chloro-2-(2-methylbenzyl)benzene 
• 89-98-5 2-chloro-benzaldehyde 

Relevant articles and documents

ZWITTERIONIC CATALYSTS FOR (TRANS)ESTERIFICATION: APPLICATION IN FLUOROINDOLE-DERIVATIVES AND BIODIESEL SYNTHESIS

An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.

Rhodium-Catalyzed Reductive Esterification Using Carbon Monoxide as a Reducing Agent

Carbon monoxide used to have a limited number of applications in organic chemistry, but it gradually increases its role as a mild and selective reducing agent. It can be applied for the carbon–heteroatom single bond formation via the reductive addition of hydrogen-containing nucleophiles to carbonyl compounds. In this paper, rhodium-catalyzed reductive esterification is described, and a comparative study of the rhodium and ruthenium catalysis in the reductive addition reactions is provided. Rhodium performs better on highly nucleophilic substrates and ruthenium is better for compounds with less nucleophilicity.

Bu 4 NI-Catalyzed C-C Bond Cleavage and Oxidative Esteri??cation of Allyl Alcohols with Toluene Derivatives

A novel oxidative esterification of 1-arylprop-2-en-1-ols with toluene derivatives catalyzed by tetrabutylammonium iodide (TBAI) is reported. The optimization of the reaction conditions illustrates that each of experiment parameters including the catalyst, solvent, and oxidant is significant for present oxidative functionalization. This metal-free protocol has a broad substrate scope including the halogen groups for further functionalization and enriches the reactivity profile of allyl alcohol and toluene derivatives. In addition, this protocol represents a new transformation of allyl alcohol involving C-C bond cleavage and C-O bond forming.