106822-42-8

Basic information

• Product Name: Heptabenzyl-α-D-glucogallin
• Synonyms: Heptabenzyl-α-D-glucogallin
• CAS NO: 106822-42-8
• Molecular Weight: 963.137
• Mol File: 106822-42-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Heptabenzyl-α-D-glucogallin(CAS DataBase Reference)
• NIST Chemistry Reference: Heptabenzyl-α-D-glucogallin(106822-42-8)
• EPA Substance Registry System: Heptabenzyl-α-D-glucogallin(106822-42-8)

Safety Data

• Hazardous Substances Data: 106822-42-8(Hazardous Substances Data)

Upstream product

• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 1486-48-2 3,4,5-tribenzyloxybenzoic acid 
• 1486-47-1 3,4,5-tris(benzyloxy)benzoyl chloride 

Downstream Products

• 53318-36-8 1-O-galloyl-α-D-glucopyranose 
• 20905-74-2 3,5-di-O-β-D-glucopyranoside of cyanidin 
• 13405-60-2 β-glucogallin 

Relevant articles and documents

Gallotannins and Tannic Acid: First Chemical Syntheses and in Vitro Inhibitory Activity on Alzheimer's Amyloid β-Peptide Aggregation

The screening of natural products in the search for new lead compounds against Alzheimer's disease has unveiled several plant polyphenols that are capable of inhibiting the formation of toxic β-amyloid fibrils. Gallic acid based gallotannins are among these polyphenols, but their antifibrillogenic activity has thus far been examined using "tannic acid", a commercial mixture of gallotannins and other galloylated glucopyranoses. The first total syntheses of two true gallotannins, a hexagalloylglucopyranose and a decagalloylated compound whose structure is commonly used to depict "tannic acid", are now described. These depsidic gallotannins and simpler galloylated glucose derivatives all inhibit amyloid β-peptide (Aβ) aggregation invitro, and monogalloylated α-glucogallin and a natural β-hexagalloylglucose are shown to be the strongest inhibitors.