1069137-36-5Relevant articles and documents
An efficient route to polynitrogen-fused tricycles via a nitrene-mediated N-N bond formation under microwave irradiation
Nyffenegger, Coralie,Pasquinet, Eric,Suzenet, Franck,Poullain, Didier,Jarry, Christian,Léger, Jean-Michel,Guillaumet, Gérald
, p. 9567 - 9573 (2008)
The synthesis of unprecedented fused azaheterocyclic ring systems is described. Tricycles with either a central pyrazole or a triazole ring were obtained via a nitrene-mediated reaction of nitro bis(hetaryl) derivatives in the presence of triethylphosphite. The cyclization proceeded with complete chemoselectivity for the desired N-N bond formation and was completed within minutes under microwave activation. The key nitro bicycles were synthesized using either Stille couplings or aromatic nucleophilic substitution.