1070687-43-2

Basic information

• Product Name: N-(bis(4-fluorophenyl)methyl)-4-methylbenzenesulfonamide
• Synonyms: N-(bis(4-fluorophenyl)methyl)-4-methylbenzenesulfonamide
• CAS NO: 1070687-43-2
• Molecular Weight: 373.423
• Mol File: 1070687-43-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(bis(4-fluorophenyl)methyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(bis(4-fluorophenyl)methyl)-4-methylbenzenesulfonamide(1070687-43-2)
• EPA Substance Registry System: N-(bis(4-fluorophenyl)methyl)-4-methylbenzenesulfonamide(1070687-43-2)

Safety Data

• Hazardous Substances Data: 1070687-43-2(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 352-13-6 4-flourophenylmagnesium bromide 
• 457-68-1 4,4'-difluorodiphenylmethane 
• 70-55-3 toluene-4-sulfonamide 
• 365-24-2 4,4'-difluorobenzhydryl alcohol 

Relevant articles and documents

Halogen-Bond-Induced Consecutive Csp3-H Aminations via Hydrogen Atom Transfer Relay Strategy

The utilization of a halogen bond in a number of chemical fields is well-known. Surprisingly, the incorporation of this useful noncovalent interaction in chemical reaction engineering is rare. We disclose here an uncommon use of halogen bonding to induce intermolecular Csp3-H amination while enabling a hydrogen atom transfer relay strategy to access privileged pyrrolidine structures directly from alkanes. Mechanistic studies support the presence of multiple halogen bond interactions at distinct reaction stages.

Au(iii)-catalyzed intermolecular amidation of benzylic C-H bonds

Au(iii)-catalyzed intermolecular amidations of benzylic C-H bonds with sulfonamides and carboxamides are described. The protocol with the Au-bipy complex/N-bromosuccinimide system provides practical applications for synthesis of various amides via C-H activations. The reaction proceeds with high efficiency to give the corresponding amines, which are extremely useful synthetic intermediates.