107220-26-8 Usage
Description
1-Azabicyclo[2.2.2]octan-3-ol,3-(mercaptomethyl)is a light yellow powder that serves as an intermediate in the preparation of Cevimeline and its respective derivatives. It is a unique chemical compound with a complex structure, characterized by its azabicyclo ring system and the presence of a mercaptomethyl group.
Uses
Used in Pharmaceutical Industry:
1-Azabicyclo[2.2.2]octan-3-ol,3-(mercaptomethyl)is used as an intermediate in the synthesis of Cevimeline, a medication used to treat dry mouth (xerostomia) caused by various conditions such as Sj?gren's syndrome or as a side effect of certain medications. The compound plays a crucial role in the development of this therapeutic agent, contributing to its effectiveness in alleviating symptoms and improving the quality of life for patients.
Used in Chemical Synthesis:
1-Azabicyclo[2.2.2]octan-3-ol,3-(mercaptomethyl)is also used as a key intermediate in the preparation of various derivatives, which can be further utilized in the development of new pharmaceuticals, agrochemicals, or other specialty chemicals. Its unique structure and functional groups make it a valuable building block for the synthesis of a wide range of compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 107220-26-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,2,2 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 107220-26:
(8*1)+(7*0)+(6*7)+(5*2)+(4*2)+(3*0)+(2*2)+(1*6)=78
78 % 10 = 8
So 107220-26-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NOS/c10-8(6-11)5-9-3-1-7(8)2-4-9/h7,10-11H,1-6H2
107220-26-8Relevant articles and documents
A new route to cevimeline
Pramanik, Chinmoy,Patil, Pradip,Kotharkar, Sandeep,Tripathy, Narendra K.,Gurjar, Mukund K.
, p. 3043 - 3045 (2013/06/27)
The present work demonstrates a new route for the synthesis of cevimeline in which safe and odorless thiourea is utilized as a thiolating reagent.
Method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine
-
, (2008/06/13)
A method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine, which comprises reacting 3-hydroxy-3-mercaptomethylquinuclidine or a salt thereof and a carbonyl compound in the presence of a catalyst made of at least one member selected from the group consisting of tin halides, oxyacids of phosphorus, phosphorus oxyhalides and organic sulfonic acids, to produce cis-form 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine or a salt thereof.
