107220-30-4

Basic information

• Product Name: 2-Diphenylmethylspiro (1,3-oxathiolane-5,3') quinuclidine
• Synonyms: 2-Diphenylmethylspiro (1,3-oxathiolane-5,3') quinuclidine
• CAS NO: 107220-30-4
• Molecular Weight: 351.513
• Mol File: 107220-30-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Diphenylmethylspiro (1,3-oxathiolane-5,3') quinuclidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Diphenylmethylspiro (1,3-oxathiolane-5,3') quinuclidine(107220-30-4)
• EPA Substance Registry System: 2-Diphenylmethylspiro (1,3-oxathiolane-5,3') quinuclidine(107220-30-4)

Safety Data

• Hazardous Substances Data: 107220-30-4(Hazardous Substances Data)

Upstream product

• 7647-01-0 hydrogenchloride 
• 107220-26-8 3-hydroxy-3-(mercaptomethyl)quinuclidine 
• 947-91-1 Diphenylacetaldehyde 

Relevant articles and documents

Dry skin remedies

Novel dry skin remedies useful for treatment dry skin, containing as the active ingredient spiro [oxathiolane-quinuclidine] derivatives represented by general formula (I) or acid addition salts thereof, desirably cis-2-methylspiro [1,3-oxathiolane-5,3′-quinuclidine] hydrochloride. The remedies promote the secretion of sebaceous and sweat glands through oral or parenteral administration to treat dry skin, thus being useful as drugs.

Composition and method for treating Sjoegren syndrome disease

A composition for treating a Sjoegren syndrome disease is disclosed. The composition comprising derivative of spirooxathiolane-quinuclidine of the following formula (I), STR1 wherein Z is CR 1 R 2, wherein R 1 and R 2 may be the same or different and each represents hydrogen, alkyl, cyclopentyl, cyclohexyl, aryl, diarylmethylol, or alkyl which may be substituted by one or more aryl groups, or an acid addition salt thereof, or an acid addition salt thereof, as an effective component. Especially effective is an administration of a hydrochloric acid addition salt of 2-methylspiro(1,3-oxathiolane-5,3'')quinuclidine.