1075-11-2 Usage
General Description
6-Fluoroisoquinoline is a chemical compound with the molecular formula C9H6FN. It is a fluorinated derivative of isoquinoline, which is commonly used as a building block in the synthesis of biologically active compounds and pharmaceuticals. 6-Fluoroisoquinoline has a wide range of applications and is often used as a precursor in the production of various drugs and agrochemicals. It is also used in research and development to create new molecules with potential therapeutic benefits. Additionally, 6-Fluoroisoquinoline is utilized as a fluorescent probe in analytical chemistry and bioimaging studies. However, it is important to handle this compound with care as it is toxic and potentially harmful if ingested or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 1075-11-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,7 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1075-11:
(6*1)+(5*0)+(4*7)+(3*5)+(2*1)+(1*1)=52
52 % 10 = 2
So 1075-11-2 is a valid CAS Registry Number.
1075-11-2Relevant articles and documents
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Bellas,Suschitzky
, p. 4561,4564 (1964)
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Pd-catalyzed nucleophilic fluorination of aryl bromides
Lee, Hong Geun,Milner, Phillip J.,Buchwald, Stephen L.
supporting information, p. 3792 - 3795 (2014/04/03)
On the basis of mechanism-driven reaction design, a Pd-catalyzed nucleophilic fluorination of aryl bromides and iodides has been developed. The method exhibits a broad substrate scope, especially with respect to nitrogen-containing heteroaryl bromides, and proceeds with minimal formation of the corresponding reduction products. A facilitated ligand modification process was shown to be critical to the success of the reaction.
CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLONE DERIVATIVES
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Page/Page column 44, (2008/12/06)
The invention relates to 6-substituted isoquinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and composit