108-16-7 Usage
Description
1-Dimethylamino-2-propanol (1DMA2P, DMAPH) is a tertiary amine and a dimethylamino-alcohol with a high boiling point. It is characterized by its light yellow liquid appearance and is known for its potent protective properties against mechlorethamine cytotoxicity and its role as an inhibitor of choline uptake. The kinetics of the homogeneous reaction of carbon dioxide (CO2) with 1-Dimethylamino-2-propanol in water has been studied using a stopped-flow technique.
Uses
1. Used in Forensic Chemistry:
1-Dimethylamino-2-propanol is used as a compound for identifying the illegal manufacture of methadone. Its presence can be indicative of clandestine drug production processes, making it a valuable tool in forensic chemistry for detecting and preventing the illegal production of controlled substances.
2. Used in Pharmaceutical Research:
As a potent protector against mechlorethamine cytotoxicity, 1-Dimethylamino-2-propanol is used in pharmaceutical research to develop new drugs and therapies that can mitigate the harmful effects of certain chemotherapy agents. This application is particularly relevant in the development of treatments for cancer and other diseases that involve the use of cytotoxic drugs.
3. Used in Neurochemistry:
1-Dimethylamino-2-propanol serves as an inhibitor of choline uptake, making it a useful compound in neurochemical research. By inhibiting choline uptake, it can help researchers understand the role of choline in various neurological processes and develop potential treatments for conditions related to choline metabolism or neurotransmission.
4. Used in Environmental Chemistry:
The study of the kinetics of the homogeneous reaction of carbon dioxide (CO2) with 1-Dimethylamino-2-propanol in water using a stopped-flow technique contributes to the understanding of CO2 sequestration and its interaction with various chemicals. This knowledge can be applied in environmental chemistry to develop methods for reducing CO2 emissions and mitigating the effects of climate change.
5. Used in Chemical Synthesis:
Due to its unique chemical properties, 1-Dimethylamino-2-propanol can be used as a reagent or intermediate in the synthesis of various organic compounds. Its ability to participate in a wide range of chemical reactions makes it a valuable component in the development of new materials and pharmaceuticals.
Flammability and Explosibility
Flammable
Check Digit Verification of cas no
The CAS Registry Mumber 108-16-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 108-16:
(5*1)+(4*0)+(3*8)+(2*1)+(1*6)=37
37 % 10 = 7
So 108-16-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H13NO/c1-5(7)4-6(2)3/h5,7H,4H2,1-3H3/p+1/t5-/m1/s1
108-16-7Relevant articles and documents
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Nikitskaya,E.S. et al.
, (1967)
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Low-Temperature Reductive Aminolysis of Carbohydrates to Diamines and Aminoalcohols by Heterogeneous Catalysis
Pelckmans, Michiel,Vermandel, Walter,Van Waes, Frederik,Moonen, Kristof,Sels, Bert F.
, p. 14540 - 14544 (2017/10/23)
Short amines, such as ethanolamines and ethylenediamines, are important compounds in today's bulk and fine chemicals industry. Unfortunately, current industrial manufacture of these chemicals relies on fossil resources and requires rigorous safety measures when handling explosive or toxic intermediates. Inspired by the elegant working mechanism of aldolase enzymes, a novel heterogeneously catalyzed process—reductive aminolysis—was developed for the efficient production of short amines from carbohydrates at low temperature. High-value bio-based amines containing a bio-derived C2 carbon backbone were synthesized in one step with yields up to 87 C%, in the absence of a solvent and at a temperature below 405 K. A wide variety of available primary and secondary alkyl- and alkanolamines can be reacted with the carbohydrate to form the corresponding C2-diamine. The presented reductive aminolysis is therefore a promising strategy for sustainable synthesis of short, acyclic, bio-based amines.
Aminimide derived from benzoylformic acid ester as photolatent base/radical initiator
Kirino, Manabu,Tomita, Ikuyoshi
experimental part, p. 1556 - 1563 (2012/06/04)
An aminimide possessing a benzoyl substituent, 1,1-dimethyl-1-(2- hydroxypropyl)amine benzoylformimide (BFI), proved to serve as an excellent photobase catalyst. BFI decomposes smoothly by the UV irradiation to give products containing tertiary amines. The effective nature of BFI as a photo/thermal dual-base catalyst was convinced by the thermal and photoinduced polymerization of epoxide/thiol system. Based on the facts that the mixture of BFI and epoxide/thiol exhibit a long pot life in dark and that it undergoes smooth polymerization by UV irradiation and heating, it was supported that BFI serves as an efficient photo/thermal latent dual-base catalysts. It was also found that BFI initiates the free radical polymerization of vinyl monomers such as 2-hydroxylethyl methacrylate (HEMA) under the UV irradiation while the mixture of BFI and HEMA also exhibit a long pot life in dark, indicating the excellent ability of BFI as a photoradical initiator.
Processes for the preparation of aminoethers
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, (2008/06/13)
A process for preparing aminoethers, particularly bis[2-(N,N-dialkylamino)alkyl]ethers, which comprises contacting a carboxylated aminoether with a metal oxide catalyst under conditions effective to produce the aminoether. Many of these aminoethers are useful as catalysts in the production of polyurethanes, especially cellular polyurethanes.
