108124-04-5

Basic information

• Product Name: 4-oxo-2-phenyl-2-cyclohexene-1-carboxylic acid ethyl ester
• Synonyms: 4-oxo-2-phenyl-2-cyclohexene-1-carboxylic acid ethyl ester
• CAS NO: 108124-04-5
• Molecular Weight: 244.29
• Mol File: 108124-04-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-oxo-2-phenyl-2-cyclohexene-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-2-phenyl-2-cyclohexene-1-carboxylic acid ethyl ester(108124-04-5)
• EPA Substance Registry System: 4-oxo-2-phenyl-2-cyclohexene-1-carboxylic acid ethyl ester(108124-04-5)

Safety Data

• Hazardous Substances Data: 108124-04-5(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 92582-13-3 2-(phenylcarbonyl)-5-oxohexanoate 
• 199106-77-9 ethyl 2-hydroxy-4-oxo-2-phenylcyclohexanecarboxylate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 10345-87-6 3-phenylcyclohex-2-enone 
• 259822-92-9 ethyl 3-methyl-4-oxo-2-phenylcyclohex-2-enecarboxylate 
• 1453494-36-4 C₁₅H₁₇NO₃ 

Relevant articles and documents

Process for preparing (hetero) aromatic substituted benzene derivatives

Three processes are described for preparing (hetero)aromatic substituted benzene derivatives which comprise aromatization of cyclohexenone derivatives via (chloro)cyclohexadiene derivatives.

Studies on alkylation of Hagemann's ester and its derivatives with alkyl halides and Michael acceptors

Alkylation and Michael addition of ethyl 3-methyl-4-oxo-2-phenylcyclohex-2-enecarboxylate (1b) have been studied under basic conditions. Similar reactions with Hagemann's ester (1c) have been carried out using phase transfer catalysts as well as solid supports. The ratio of the C-1 to C-3 alkylated products have been determined. A probable explanation for the regioselectivity observed has been given.