108436-36-8 Usage
Description
2'-Monodehydroxy-2'-chloro Ganciclovir, also known as Iso mono chloro ganciclovir, is an impurity of Ganciclovir (G235000) and a sugar-modified acyclic analogue of guanosine (G837900). It has been found to possess potential virucidal activity, making it a compound of interest in the field of antiviral research.
Uses
Used in Pharmaceutical Industry:
2'-Monodehydroxy-2'-chloro Ganciclovir is used as an impurity in the production of Ganciclovir (G235000) for its potential virucidal activity. 2'-Monodehydroxy-2'-chloro Ganciclovir may contribute to the development of new antiviral therapies and treatments.
Used in Antiviral Research:
2'-Monodehydroxy-2'-chloro Ganciclovir is used as a research compound to study its potential virucidal activity. This could lead to the discovery of new antiviral agents and the improvement of existing treatments for various viral infections.
Used in Drug Development:
As a sugar-modified acyclic analogue of guanosine (G837900), 2'-Monodehydroxy-2'-chloro Ganciclovir may be utilized in the development of novel drugs targeting viral replication and infection processes. Its unique structure and potential virucidal properties make it a valuable candidate for further investigation and application in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 108436-36-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,4,3 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 108436-36:
(8*1)+(7*0)+(6*8)+(5*4)+(4*3)+(3*6)+(2*3)+(1*6)=118
118 % 10 = 8
So 108436-36-8 is a valid CAS Registry Number.
108436-36-8Relevant articles and documents
The syntheses of purine and pyrimidine secoribo-nucleosides: Acyclo-uridine derivative of cyclophosphamide
Zakerinia,Davary,Hakimelahi
, p. 912 - 915 (1990)
The synthesis of secoribo-nucleoside analogues is described. Compounds 4 and 5 possess interesting antiviral effects in vitro. A procedure is also developed for the conversion of acyclo-uridine nucleoside 7 to a novel derivative of cyclophosphamide 8.
Synthesis and anti-herpes-virus activity of acyclic 2'-deoxyguanosine analogues related to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine
Martin,McGee,Jeffrey,Hobbs,Smee,Matthews,Verheyden
, p. 1384 - 1389 (2007/10/02)
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