194154-40-0 Usage
Description
N-[(Phenylmethoxy)carbonyl]-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester is a complex organic compound with a unique chemical structure. It is characterized by its white solid appearance and is primarily used in the field of organic synthesis due to its versatile chemical properties.
Uses
1. Used in Organic Synthesis:
N-[(Phenylmethoxy)carbonyl]-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the formation of new chemical bonds and the creation of a wide range of molecules with different properties and applications.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-[(Phenylmethoxy)carbonyl]-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester is used as a building block for the development of new drugs. Its chemical properties make it a valuable component in the design and synthesis of novel therapeutic agents, potentially targeting a variety of medical conditions.
3. Used in Research and Development:
N-[(Phenylmethoxy)carbonyl]-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester is also utilized in research and development settings, where it can be employed to study the mechanisms of various biological processes and to develop new methodologies for chemical synthesis. Its unique structure and reactivity make it an interesting subject for scientific investigation and potential innovation in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 194154-40-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,1,5 and 4 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 194154-40:
(8*1)+(7*9)+(6*4)+(5*1)+(4*5)+(3*4)+(2*4)+(1*0)=140
140 % 10 = 0
So 194154-40-0 is a valid CAS Registry Number.
194154-40-0Relevant articles and documents
Synthetic method of valganciclovir hydrochloride
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Paragraph 0015; 0039; 0040, (2021/04/17)
The invention discloses a method for synthesizing valganciclovir hydrochloride, which comprises the following steps: with 1,3-dichloro-2-acetoxymethoxypropane as an initial raw material, preparing monochlorinated ganciclovir, and carrying out esterification, hydrolysis and deprotection salification to finally obtain the valganciclovir hydrochloride. The invention provides a synthesis method of siganciclovir hydrochloride, which avoids the problem of separation and conversion of N-7 and N-9 isomers in the diacetyl guanine condensation process. The method directly synthesizes monochlorinated ganciclovir without using ganciclovir, instead of the synthesis of monoacetyl ganciclovir in the prior art, so that the method avoids the problem of diester compound separation caused by ganciclovir residues, has the advantages of short process steps, simple operation, convenient purification and low cost, is beneficial to industrial production, and is suitable for synthesis of valganciclovir hydrochloride.
PREPARATION OF VALGANCICLOVIR AND ITS SALTS
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Page/Page column 9, (2011/09/16)
The application relates to processes for preparing valganciclovir and pharmaceutically acceptable salts thereof, as well as intermediates for the processes. valganciclovir hydrochloride is represented by Formula II.
Preparation of ester of purine derivatives
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Page/Page column 7, (2008/06/13)
A process for the preparation of valganciclovir with triacetyl ganciclovir (V) as a starting material, comprising the following steps: selective hydrolysis, reacting with a coupling agent and a solvent, followed by hydrolysis under basic conditions and hydrogenolysis in the presence of a catalyst.
