1086561-21-8

Basic information

• Product Name: 2-(4-methyl-pyridin-3-yl)-benzaldehyde
• Synonyms: 2-(4-methyl-pyridin-3-yl)-benzaldehyde
• CAS NO: 1086561-21-8
• Molecular Weight: 197.236
• Mol File: 1086561-21-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-methyl-pyridin-3-yl)-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methyl-pyridin-3-yl)-benzaldehyde(1086561-21-8)
• EPA Substance Registry System: 2-(4-methyl-pyridin-3-yl)-benzaldehyde(1086561-21-8)

Safety Data

• Hazardous Substances Data: 1086561-21-8(Hazardous Substances Data)

Upstream product

• 40138-16-7 2-formylbenzene boronic acid 
• 3430-22-6 3-Bromo-4-methylpyridin 

Downstream Products

• 1086561-62-7 3-(2-[1,3]dioxolan-2-yl-phenyl)-4-methyl-pyridine 

Relevant articles and documents

Intramolecular Acylation of Unactivated Pyridines or Arenes via Multiple C-H Functionalizations: Synthesis of All Four Azafluorenones and Fluorenones

An unprecedented intramolecular acylation of unactivated pyridines via multiple C(sp3/sp2)-H functionalizations of a methyl, hydroxymethyl, or aldehyde group has been developed providing a general access to all four azafluorenones. The application of this protocol is further demonstrated to the synthesis of azafluorenone related fused nitrogen heterocycles and fluorenones. In addition, design and synthesis of a novel fluorene based organic emitter for potential use in organic light emitting devices (OLEDs) is also reported.

A general and efficient method for the synthesis of benzo-(iso)quinoline derivatives

A new, short and efficient synthesis of substituted benzo-(iso)quinoline derivatives is reported. The methodology is based on a Suzuki or Negishi cross-coupling followed by a cyclization reaction induced by t-BuOK in DMF to form the central ring. This approach allowed the synthesis of all four benzo-(iso)quinoline isomers and the substitution of each ring of the benzo-(iso)quinoline core.