108770-97-4

Basic information

• Product Name: 4-pyridyl phenyl sulfoxide
• Synonyms: 4-pyridyl phenyl sulfoxide
• CAS NO: 108770-97-4
• Molecular Weight: 203.265
• Mol File: 108770-97-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-pyridyl phenyl sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-pyridyl phenyl sulfoxide(108770-97-4)
• EPA Substance Registry System: 4-pyridyl phenyl sulfoxide(108770-97-4)

Safety Data

• Hazardous Substances Data: 108770-97-4(Hazardous Substances Data)

Upstream product

• 5427-04-3 diphenylmethyl phenyl sufoxide 
• 7417-81-4 benzyl phenyl sulfoxide 
• 19524-06-2 4-bromopyridine hydrochloride 
• 1120-87-2 4-bromopyridin 
• 108-98-5 thiophenol 
• 33399-48-3 4-(phenylthio)pyridine 

Downstream Products

• 581-47-5 4-(2-pyridyl)pyridine 
• 945-51-7 1,1'-sulfinylbisbenzene 
• 78815-49-3 α-(3-methoxyphenyl)-4-pyridinemethanol 
• 2603-14-7 1-pyridin-4-yl-cyclopentanol 
• 127411-18-1 4-Benzenesulfinyl-3-(methoxy-phenyl-methyl)-pyridine 
• 127411-32-9 3-(Methoxy-phenyl-methyl)-[4,4']bipyridinyl 
• 127411-31-8 3'-(Methoxy-phenyl-methyl)-[3,4']bipyridinyl 
• 127411-30-7 3'-(Methoxy-phenyl-methyl)-[2,4']bipyridinyl 
• 20675-59-6 (S)-1-methyl-4-(phenylsulfinyl)benzene 
• 108771-05-7 1,3-Diphenyl-3-pyridin-4-yl-propan-1-one 
• 19490-94-9 1-phenyl-1-(pyridin-4-yl)ethan-1-ol 
• 14548-46-0 4-Benzoylpyridine 
• 91902-74-8 1-methoxy-2-(phenylsulfinyl)benzene 
• 5958-00-9 4-(2-methoxylphenyl)pyridine 

Relevant articles and documents

Diaryl sulfoxides from aryl benzyl sulfoxides: A single palladium-catalyzed triple relay process

A novel approach to produce diaryl sulfoxides from aryl benzyl sulfoxides is reported. Optimization of the reaction conditions was performed using high-throughput experimentation techniques. The [Pd(dba)2]/NiXantPhos catalyst system successfully promotes a triple relay process involving sulfoxide α-arylation, C-S bond cleavage, and C-S bond formation. The byproduct benzophenone is formed by an additional palladium-catalyzed process. It is noteworthy that palladium-catalyzed benzylative C-S bond cleavage of sulfoxides is unprecedented. A wide range of aryl benzyl sulfoxides, as well as alkyl benzyl sulfoxides with various (hetero)aryl bromides were employed in the triple relay process in good to excellent yields (85-99 %). Moreover, aryl methyl sulfoxides, dibenzyl sulfoxides, and dimethylsulfoxide could be utilized to generate diaryl sulfoxides involving multiple catalytic cycles by a single catalyst. Three for one: The [Pd(dba)2]/NiXantPhos (dba=dibenzylideneacetone) catalyst system successfully promotes a triple relay process involving sulfoxide α-arylation, C-S bond cleavage, and C-S bond formation to give diaryl sulfoxides (see picture). Aryl benzyl sulfoxides, as well as alkyl benzyl sulfoxides reacted with various (hetero)aryl bromides. Copyright