109021-59-2 Usage
Description
7-Methoxy-3-indolecarboxaldehyde is an organic compound that serves as a crucial building block in the synthesis of various pharmaceuticals. It is characterized by its indole structure with a methoxy group at the 7th position and a formyl group at the 3rd position, which contributes to its reactivity and potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Synthesis:
7-Methoxy-3-indolecarboxaldehyde is used as a reactant for the preparation of [(indolyl)methyl]hydantoin and thiohydantoin derivatives. These compounds have potential applications in the treatment of necroptosis, a form of programmed cell death that occurs in response to various cellular stressors.
Used in Anticancer Applications:
7-Methoxy-3-indolecarboxaldehyde is also used as a reactant in the synthesis of pyridyl-ethenyl-indoles, which are potential anticancer immunomodulators. These compounds may help modulate the immune system to enhance the body's response against cancer cells, potentially leading to improved treatment outcomes for cancer patients.
Check Digit Verification of cas no
The CAS Registry Mumber 109021-59-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,0,2 and 1 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 109021-59:
(8*1)+(7*0)+(6*9)+(5*0)+(4*2)+(3*1)+(2*5)+(1*9)=92
92 % 10 = 2
So 109021-59-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO2/c1-13-9-4-2-3-8-7(6-12)5-11-10(8)9/h2-6,11H,1H3
109021-59-2Relevant articles and documents
Cu-Catalyzed Dimerization of Indole Derived Oxime Acetate for Synthesis of Biimidazo[1,2- a]indoles
Xie, Tao,Sui, Qi-Bang,Qin, Lu-Zhe,Wen, Xiaoan,Sun, Hongbin,Xu, Qing-Long,Zhen, Le
supporting information, p. 5518 - 5529 (2021/05/04)
A copper-mediated cyclization and dimerization of indole derived oxime acetate was developed to generate a series of biimidazo[1,2-a]indole scaffolds with two contiguous stereogenic quaternary carbons in one step.
CELL CYCLE PROGRESSION INHIBITOR
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Paragraph 0076, (2019/09/18)
The present invention provides a cell cycle progression inhibitor, a cytostatic agent, and an anticancer agent. The cell cycle progression inhibitor, the cytostatic agent, and the anticancer agent each contains a Hes1 protein-PHB2 protein binding enhancer.
INDOLE AHR INHIBITORS AND USES THEREOF
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Paragraph 00874-00875, (2018/11/22)
The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.