1092363-46-6

Basic information

• Product Name: C₂₀H₂₅NO₄S
• Synonyms: C₂₀H₂₅NO₄S
• CAS NO: 1092363-46-6
• Molecular Weight: 375.489
• Mol File: 1092363-46-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₅NO₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₅NO₄S(1092363-46-6)
• EPA Substance Registry System: C₂₀H₂₅NO₄S(1092363-46-6)

Safety Data

• Hazardous Substances Data: 1092363-46-6(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 149286-01-1 (R)-N-(2-hydroxy-2-phenylethyl)-4-methylbenzenesulfonamide 

Downstream Products

• 1092363-51-3 C₂₉H₃₅NO₆S 

Relevant articles and documents

A straightforward synthesis of enantiopure 2,6-disubstituted morpholines by a regioselective O-protection/activation protocol

Enantiopure 2,6-disubstituted morpholines have been synthesized through the ring opening of chiral, nonracemic oxiranes with nitrogen nucleophiles, under solid-liquid phase-transfer catalysis (SL-PTC) conditions. The β-hydroxytosyl amides resulting from the ring opening of a first epoxide with TsNH2 was used as nucleophile, after protection of the hydroxyl group, in the reaction with a second oxirane. The morpholine skeleton has been generated through standard functional group chemistry, followed by cyclization of the intermediate β-hydroxy-β′-tosyloxy-tosylamides carried out under SL-PTC conditions. N-Tosyl morpholines produced can be employed as building blocks in the synthesis of pharmaceuticals and as chiral tools. Georg Thieme Verlag Stuttgart.