149286-01-1

Basic information

• Product Name: Benzenesulfonamide, N-[(2R)-2-hydroxy-2-phenylethyl]-4-methyl-
• CAS NO: 149286-01-1
• Molecular Formula: C15H17NO3S
• Molecular Weight: 291.371
• Mol File: 149286-01-1.mol
• Article Data: 42

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-[(2R)-2-hydroxy-2-phenylethyl]-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-[(2R)-2-hydroxy-2-phenylethyl]-4-methyl-(149286-01-1)
• EPA Substance Registry System: Benzenesulfonamide, N-[(2R)-2-hydroxy-2-phenylethyl]-4-methyl-(149286-01-1)

Safety Data

• Hazardous Substances Data: 149286-01-1(Hazardous Substances Data)

Upstream product

• 96-09-3 styrene oxide 
• 70-55-3 toluene-4-sulfonamide 
• 30057-92-2 N-(p-toluenesulfonyl)aminoacetophenone 
• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 7732-18-5 water 
• 1449281-72-4 4-methyl-N-(methylsulfonyl)-N-(2-oxo-2-phenylethyl)benzenesulfonamide 
• 1414869-21-8 μ-oxo-bis[(4-methyl)-N-tosylbenzenesulfonamidyl(phenyl)iodine] 
• 3695-00-9 di(4-tosyl)amine 
• 1449281-57-5 [((N-mesyl)methanesulfonamidyl) (4-methyl)-N-tosylbenzenesulfonamidyl]iodosobenzene 
• 20989-17-7 Phenylglycinol 
• 98-59-9 p-toluenesulfonyl chloride 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 133522-24-4 (R)-4-Phenyl-[1,3,2]dioxathiolane 2-oxide 
• 7568-93-6 2-Amino-1-phenylethanol 

Downstream Products

• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 17798-13-9 N-(2-chloro-2-phenylethyl)tosylamide 
• 1092363-46-6 C₂₀H₂₅NO₄S 
• 697287-96-0 4-methyl-N-(2-oxo-2-phenylethyl)-N-(prop-2-yn-1-yl)benzenesulfonamide 

Relevant articles and documents

Efficient ring opening reactions of N-tosyl aziridines with amines and water in presence of catalytic amount of cerium(IV) ammonium nitrate

While methyl- and benzylamines opened N-tosyl aziridines 1 very efficiently in acetonitrile with complete regio- and stereoselectivity to give the corresponding diamines 2 and 3, respectively, in excellent yields, similar openings with water could only be achieved in the presence of a catalytic amount of cerium(IV) ammonium nitrate under very mild conditions furnishing the amino alcohols 4.

Conversion of aziridines to oxazolidines through geminal difunctionalization of vinyl arenes or by tandem ring-opening/closing reaction of aziridine itself

One pot synthesis of 1,3-oxazolidines derivatives was developed by two different approaches. Aziridines were used in the first approach instead of amino alcohol. Whereas, in the second approach we have developed an unprecedented reaction where aziridine i

Zirconyl nitrate mediated regioselective ring opening of epoxides and aziridines: an easy synthesis of β-nitrato-alcohols and -sulfonamides

Epoxides and aziridines are cleaved efficiently and regioselectively in the presence of zirconyl nitrate at room temperature to afford the corresponding β-nitrato-alcohols and -sulfonamides, respectively, in high yields.

Cobalt-Catalyzed Hydroalkynylation of Vinylaziridines

Transition metal-catalyzed hydroalkynylation reactions are efficient transformations allowing the straightforward formation of functionalized alkynes. Therein, we disclose the cobalt-catalyzed hydroalkynylation of vinylaziridines giving rise to both linea

Double Functionalization of Styrenes by Cu-Mediated Assisted Tandem Catalysis

The double functionalization of styrenes through Cu-mediated assisted tandem catalysis was developed. The reaction was initiated by Cu-catalyzed aziridination and the subsequent nucleophilic ring-opening, which was triggered by the addition of (NH4)2S2O8 as an oxidant of Cu-catalyst to form a variety of C–C and C–X bonds. The expansion to three contiguous catalytic cycles led to the synthesis of functionalized indolines by one-pot operation.