109257-45-6

Basic information

• Product Name: 4-Pentynamide, N-phenyl-2-(2-propynyl)-
• CAS NO: 109257-45-6
• Molecular Formula: C14H13NO
• Molecular Weight: 211.263
• Mol File: 109257-45-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Pentynamide, N-phenyl-2-(2-propynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentynamide, N-phenyl-2-(2-propynyl)-(109257-45-6)
• EPA Substance Registry System: 4-Pentynamide, N-phenyl-2-(2-propynyl)-(109257-45-6)

Safety Data

• Hazardous Substances Data: 109257-45-6(Hazardous Substances Data)

Upstream product

• 40870-14-2 2-(2-propinyl)-4-pentinoyl chloride 
• 62-53-3 aniline 
• 4431-32-7 2,2-di(prop-2-ynyl)propan-1,3-dioic acid 
• 65994-70-9 dipropargylacetic acid 
• 2689-88-5 diethyl 2,2-di(prop-2-yn-1-yl)malonate 
• 112404-83-8 2-(2-propinyl)-4-pentinoyl isothiocyanate 

Downstream Products

• 23099-05-0 3-methyl-N-phenylbenzamide 

Relevant articles and documents

SELECTIVITY OF NUCLEOPHILIC ADDITION TO AND SUBSTITUTION AT ISOTHIOCYANATOCARBONYL GROUP. REACTIONS OF 4-PENTINOYL- AND 2-(2-PROPINYL)-4-PENTINOYL ISOTHIOCYANATE WITH AMINES AND METHANOL

4-Pentinoyl isothiocyanate reacts with primary and secondary amines by either nucleophilic addition to N=C=S group to yield the corresponding thioureas, or a nucleophilic substitution at the carbonyl group to give 4-pentinoic acid amides.The less nucleophilic diphenylamine reacts selectively to afford the product of nucleophilic addition only. 2-(2-Propinyl)-4-pentinoyl isothiocyanate, having a sterically hindered carbonyl group, furnished with primary amines a mixture of amides and thioureas, whereas the bulkier secondary amines react selectively to form thioureasonly.Both isothiocyanates afford with methanol as a nucleophile axclusively the corresponding O-methyl monothiocarbamates.