109453-49-8

Basic information

• Product Name: (C₈H₇O₂)(NHCHCOO)(CH₂C₆H₅)(CO₂C₂H₅)
• Synonyms: (C₈H₇O₂)(NHCHCOO)(CH₂C₆H₅)(CO₂C₂H₅)
• CAS NO: 109453-49-8
• Molecular Weight: 371.39
• Mol File: 109453-49-8.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: (C₈H₇O₂)(NHCHCOO)(CH₂C₆H₅)(CO₂C₂H₅)(CAS DataBase Reference)
• NIST Chemistry Reference: (C₈H₇O₂)(NHCHCOO)(CH₂C₆H₅)(CO₂C₂H₅)(109453-49-8)
• EPA Substance Registry System: (C₈H₇O₂)(NHCHCOO)(CH₂C₆H₅)(CO₂C₂H₅)(109453-49-8)

Safety Data

• Hazardous Substances Data: 109453-49-8(Hazardous Substances Data)

Upstream product

• 63-91-2 L-phenylalanine 
• 501-53-1 benzyl chloroformate 
• 541-41-3 chloroformic acid ethyl ester 
• 87072-42-2 Z-L-phenylalanine DCHA salt 
• 1161-13-3 N-Cbz-L-Phe 

Downstream Products

• 26049-94-5 (S)-benzyl (4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate 
• 73048-82-5 N-Benzyloxycarbonyl-L-phenylalanine N'-methylhydroxamic acid 
• 1380115-27-4 C₃₁H₃₁N₅O₂ 
• 1380115-31-0 C₃₁H₃₂BrN₅O₂ 
• 1380115-35-4 C₃₉H₃₈BrN₅O₂ 
• 1380115-34-3 C₃₉H₃₉Br₂N₅O₂ 
• 1380115-33-2 C₅₄H₅₆N₁₀O₄ 
• 1380115-32-1 C₆₂H₆₃BrN₁₀O₄ 
• 1613244-23-7 (S)-1-(3,4-dihydroquinolin-1(2H)-yl)-3-phenyl-2-(piperidin-1-yl)propan-1-one 
• 1217642-65-3 C₁₈H₂₀N₂O 
• 2537-91-9 N-benzyloxycarbonyl-L-phenylalanyl-L-tyrosine 
• 860-55-9 (2S)-2-[((2S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanoyl)amino]-3-hydroxypropanoic acid 
• 178403-40-2 Cbz-L-Phe-L-Asp-OH 
• 154484-05-6 (S)-2-benzyloxycarbonylamino-1-iodo-3-phenylpropane 

Relevant articles and documents

A Convenient One-Pot Conversion of N-Protected Amino Acids and Peptides into Alcohols

N-Protected amino acids and peptides are converted to alcohols by chemoselective reduction of their corresponding mixed anhydrides with sodium borohydride in tetrahydrofuran with dropwise addition of methanol.

Ecological base-conditioned preparation of dipeptides using unprotected α-amino acids containing hydrophilic side chains

The coupling reactions of 3-phenylpropanoic acid and Ncarboxybenzyl á-amino acids with unprotected á-amino acids containing hydrophilic side chains such as aliphatic alcohol, aromatic alcohol, thiol, carboxylic acid, and amide afforded the corresponding amides in 6696% yield without racemization via the corresponding mixed carbonic carboxylic anhydrides under basic conditions through an ecological green synthetic method.

Double axial chirality promoted asymmetric [2,3] Stevens rearrangement of N-cinnamyl l-alanine amide-derived ammonium ylides

The base-induced asymmetric [2,3] Stevens rearrangement of N-cinnamyl tetraalkylammonium ylides derived from l-alanine amides proceeds via a double axially chiral intermediate to afford the corresponding α-substituted alanine derivatives with high enantio- and diastereoselectivities. the Partner Organisations 2014.