87072-42-2

Basic information

• Product Name: Z-L-phenylalanine DCHA salt
• Synonyms: Z-L-phenylalanine DCHA salt
• CAS NO: 87072-42-2
• Molecular Weight: 480.648
• Mol File: 87072-42-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Z-L-phenylalanine DCHA salt(CAS DataBase Reference)
• NIST Chemistry Reference: Z-L-phenylalanine DCHA salt(87072-42-2)
• EPA Substance Registry System: Z-L-phenylalanine DCHA salt(87072-42-2)

Safety Data

• Hazardous Substances Data: 87072-42-2(Hazardous Substances Data)

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 63-91-2 L-phenylalanine 
• 101-83-7 N-cyclohexyl-cyclohexanamine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 90236-34-3 Z-Phe-Pro-Pro-Phe-Ile-Val-OBzl 
• 78816-88-3 (S)-methyl 2-(((S)-2-(benzyloxy)carbonylamino)-3-phenylpropanamido)-4-(methylthio)butanoate 
• 65710-54-5 Z-Phe-Val-OEt 
• 109453-49-8 (C₈H₇O₂)(NHCHCOO)(CH₂C₆H₅)(CO₂C₂H₅) 
• 4892-10-8 N-(benzyloxycarbonyl)-L-phenylalanyl-L-phenylalanine methyl ester 
• 28426-51-9 methyl ((benzyloxy)carbonyl)-L-phenylalanyl-L-prolinate 
• 3850-45-1 Cbz-L-Phe-L-Leu-OMe 
• 60644-13-5 Z-Phe-Ala-OEt 
• 2778-34-9 ethyl [(2S)-2-(benzyloxycarbonylamino)-3-phenylpropanoylamino]acetate 
• 28944-94-7 (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanamido)propanoate 
• 5184-17-8 N-benzyloxycarbonyl-L-phenylalanylglycine methyl ester 

Relevant articles and documents

METHOD FOR SYNTHESIZING OPTICALLY ACTIVE a-AMINO ACID USING CHIRAL METAL COMPLEX COMPRISING AXIALLY CHIRAL N-(2-ACYLARYL)-2-[5,7-DIHYDRO-6H-DIBENZO[c,e]AZEPIN-6-YL] ACETAMIDE COMPOUND AND AMINO ACID

Objects of the present invention are to provide an industrially applicable method for producing an optically active α-amino acid in high yield and in a highly enantioselective manner, to provide a simple production method of an optically active α,α-disubstituted α-amino acid, and to provide an intermediate useful for the above production methods of an optically active α-amino acid and an optically active α,α-disubstituted α-amino acid. The present invention provides a production method of an optically active α-amino acid or a salt thereof, the production method comprising introducing a substituent into the α carbon in the α-amino acid moiety of a metal complex represented by the following Formula (1): by an alkylation reaction, an aldol reaction, the Michael reaction, or the Mannich reaction, and releasing an optically pure α-amino acid enantiomer or a salt thereof by acid decomposition of the metal complex.

METHOD FOR SYNTHESIZING OPTICALLY ACTIVE α-AMINO ACID USING CHIRAL METAL COMPLEX COMPRISING AXIALLY CHIRAL N-(2-ACYLARYL)-2-[5,7-DIHYDRO-6H-DIBENZO[c,e]AZEPIN-6-YL]ACETAMIDE COMPOUND AND AMINO ACID

Objects of the present invention are to provide an industrially applicable method for producing an optically active ±-amino acid in high yield and in a highly enantioselective manner, to provide a simple production method of an optically active ±,±-disubstituted ±-amino acid, and to provide an intermediate useful for the above production methods of an optically active ±-amino acid and an optically active ±,±-disubstituted ±-amino acid. The present invention provides a production method of an optically active ±-amino acid or a salt thereof, the production method comprising introducing a substituent into the ± carbon in the ±-amino acid moiety of a metal complex represented by the following Formula (1): by an alkylation reaction, an aldol reaction, the Michael reaction, or the Mannich reaction, and releasing an optically pure ±-amino acid enantiomer or a salt thereof by acid decomposition of the metal complex.