109772-08-9

Basic information

• Product Name: N-Methyl-N-(p-chlorophenyl)hydrazone of Cyclohexanone
• CAS NO: 109772-08-9
• Molecular Weight: 236.744
• Mol File: 109772-08-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Methyl-N-(p-chlorophenyl)hydrazone of Cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyl-N-(p-chlorophenyl)hydrazone of Cyclohexanone(109772-08-9)
• EPA Substance Registry System: N-Methyl-N-(p-chlorophenyl)hydrazone of Cyclohexanone(109772-08-9)

Safety Data

• Hazardous Substances Data: 109772-08-9(Hazardous Substances Data)

Upstream product

• 1007-19-8 4-chloro-N-methyl-N-nitrosoaniline 
• 108-94-1 cyclohexanone 
• 52263-26-0 N₁-(p-chlorophenyl)-N₁-methylhydrazine 

Relevant articles and documents

MECHANISM OF THE FISCHER INDOLE SYNTHESIS. QUANTUM-CHEMICAL INTERPRETATION OF THE REARRANGEMENT OF SUBSTITUTED CYCLOHEXANONE ARYLHYDRAZONES TO TETRAHYDROCARBAZOLES

Calculations of a number of model structures within the scheme of Fischer indole synthesis were made on the basis of a bonding variant of perturbation theory in the self-consistent-field (SCF) MO LCAO method.A quantum-chemical interpretation of the effect of substituents on the course of the thermal process is given.The kinetics of the thermal and acid-catalyzed indolization of substituted cyclohexanone arylhydrazones to tetrahydrocarbazoles were studied by spectrophotometry.It was shown that the experimental data are in satisfactory agreement with the calculated values. It was concluded that a concerted mechanism ( a -sigma-tropic shift) for the step involving the formation of a carbon-carbon bond in the Fischer reaction is preferred.