52263-26-0

Basic information

• Product Name: Hydrazine, 1-(4-chlorophenyl)-1-methyl-
• Synonyms: Hydrazine,(4-chlorophenyl)methyl;Hydrazine,1-(4-chlorophenyl)-1-methyl
• CAS NO: 52263-26-0
• Molecular Formula: C7H9ClN2
• Molecular Weight: 156.615
• Mol File: 52263-26-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 261.3±23.0 °C(Predicted)
• Density: 1.237±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Hydrazine, 1-(4-chlorophenyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazine, 1-(4-chlorophenyl)-1-methyl-(52263-26-0)
• EPA Substance Registry System: Hydrazine, 1-(4-chlorophenyl)-1-methyl-(52263-26-0)

Safety Data

• Hazardous Substances Data: 52263-26-0(Hazardous Substances Data)

Upstream product

• 932-96-7 N-methyl(p-chloroaniline) 
• 106-46-7 para-dichlorobenzene 
• 909253-27-6 N'-Benzhydrylidene-N-(4-chlorophenyl)-N-methylhydrazine 
• 1007-19-8 4-chloro-N-methyl-N-nitrosoaniline 
• 1073-69-4 N-4-chlorophenylhydrazine 
• 74-88-4 methyl iodide 

Downstream Products

• 85728-63-8 C-(4-nitrophenyl)-N-(4-chlorophenyl)-N-methylhydrazone 
• 909253-25-4 C₂₉H₃₄ClN₇O₃S 
• 909253-23-2 N-{5-[N'-(4-chlorophenyl)-N'-methylhydrazinocarbonyl]-1H-thieno[2,3-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl)benzamide 
• 99768-31-7 6-chloro-3-phenylbenzo[e][1,2,4]triazine 
• 843673-96-1 C₁₇H₁₆ClN 
• 109772-08-9 N-Methyl-N-(p-chlorophenyl)hydrazone of Cyclohexanone 

Relevant articles and documents

Cobalt-Catalyzed, Directed Intermolecular C-H Bond Functionalization for Multiheteroatom Heterocycle Synthesis: The Case of Benzotriazine

Transition-metal-catalyzed, directed intermolecular C-H bond functionalization is synthetically useful but heavily underexplored in multiheteroatom heterocycle synthesis. Herein we report a cobalt catalytic method for the formation of a three-nitrogen-bearing benzotriazine scaffold via the coupling of arylhydrazine and oxadiazolone. This synthetic protocol features a low-cost base metal catalyst, a maximum number of heteroatoms built into a heterocycle, a distinct synthetic logic for benzotriazines, a superior step economy, and a broad substrate scope.

A Versatile, Traceless C-H Activation-Based Approach for the Synthesis of Heterocycles

A versatile, traceless C-H activation-based approach for the synthesis of diversified heterocycles is reported. Rh(III)-catalyzed, N-amino-directed C-H alkenylation generates either olefination products or indoles (in situ annulation) in an atom- and step-economic manner at room temperature. The remarkable reactivity endowed by this directing group enables scale-up of the reaction to a 10 g scale at a very low catalyst loading (0.01 mol %/0.1 mol %). Ex situ annulation of olefination product provides entry into an array of heterocycles.

Hydrazinocarbonyl-thieno[2,3-C]pyrazoles, Process for Preparing Them, Compositions Containing Them and Use Thereof

The present invention concerns hydrazinocarbonyl-thieno[2,3-c]pyrazoles of formula (I): wherein R1, R3, R4, are R5 are as defined in the disclosure; their preparation method, compositions containing the same and their use for the treatment of pathological conditions, in particular as anticancer agents.