110166-75-1

Basic information

• Product Name: Benzoic acid, 2-(1-hexynyl)-, ethyl ester
• CAS NO: 110166-75-1
• Molecular Formula: C15H18O2
• Molecular Weight: 230.307
• Mol File: 110166-75-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(1-hexynyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(1-hexynyl)-, ethyl ester(110166-75-1)
• EPA Substance Registry System: Benzoic acid, 2-(1-hexynyl)-, ethyl ester(110166-75-1)

Safety Data

• Hazardous Substances Data: 110166-75-1(Hazardous Substances Data)

Upstream product

• 1093198-48-1 C₂₁H₂₂O₂ 
• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 693-02-7 hex-1-yne 

Downstream Products

• 132-90-1 3-n-butyl-1(2H)-isoquinolinone 

Relevant articles and documents

Oxypalladation Initiating the Oxid-ative Heck Reaction with Alkenyl -Alcohols: Synthesis of Isocoumarin–Alkanones

Highly regioselective nucleopalladation for the oxidative coupling of internal alkynes with alkenyl alcohols by using green and low-costing oxygen as the sole oxidant was investigated. This one-pot cascade cyclization proceeds through Pd-catalyzed intramolecular C–O bond cyclization, insertion of nonbiased alkenyl alcohols, β-H elimination, and reinsertion of a HPdX species, which is finally transferred to the target ketones. This method has the advantages of mild conditions, good functional group tolerance, and can be performed with unactivated alkenes to afford isocoumarin derivatives.

Condensed heteroaromatic ring systems. VIII. Synthesis of 3-substituted isocoumarins from o-halobenzoic acid derivatives

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