132-90-1

Basic information

• Product Name: 3-butylisoquinolin-1(2H)-one
• CAS NO: 132-90-1
• Molecular Formula: C₁₃H₁₅NO
• Molecular Weight: 201.2643
• Mol File: 132-90-1.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 394.8°C at 760 mmHg
• Flash Point: 236.3°C
• Density: 1.055g/cm³
• Vapor Pressure: 1.92E-06mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: 3-butylisoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-butylisoquinolin-1(2H)-one(132-90-1)
• EPA Substance Registry System: 3-butylisoquinolin-1(2H)-one(132-90-1)

Safety Data

• Hazardous Substances Data: 132-90-1(Hazardous Substances Data)

Upstream product

• 146470-69-1 (+/-)-3-butyl-3,4-dihydroisoquinolin-1-(2H)-one 
• 855619-99-7 3-butyl-4-hydroxy-3,4-dihydro-2H-isoquinolin-1-one 
• 859629-10-0 3-(1-amino-pentyl)-phthalide 
• 30531-69-2 3-butylisochromen-1-one 
• 110166-74-0 2-(hex-1-yn-1-yl)benzamide 
• 151475-49-9 N-propenyl-3-butylisoquinolin-1(2H)-one 
• 148991-89-3 N-Methoxy-3-butylisoquinolin-1(2H)-one 
• 110166-78-4 2-(hex-1-yn-1-yl)benzonitrile 
• 615-42-9 1,2-Diiodobenzene 
• 693-02-7 hex-1-yne 
• 253435-14-2 1-iodo-2-(hex-1-ynyl)benzene 
• 2042-37-7 o-cyanobromobenzene 
• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 110166-75-1 ethyl 2-(hex-1-yn-1-yl)benzoate 

Downstream Products

• 86-80-6 dimethisoquin 

Relevant articles and documents

Direct access to cobaltacycles via C-H activation: N-chloroamide- enabled room-temperature synthesis of heterocycles

Cobaltacycle synthesis via C-H activation has been achieved for the first time, providing key mechanistic insight into cobalt catalytic chemistry. NChloroamides are used as a directing synthon for cobalt-catalyzed roomtemperature C-H activation and construction of heterocycles. Alkynes as coupling partners allow convenient access to isoquinolones, a class of synthetically and pharmaceutically important compounds. The broad substrate scope enables a diverse range of substitution patterns to be incorporated into the heterocyclic scaffold.

A dramatic substituent effect in silver(I)-catalyzed regioselective cyclization of ortho-alkynylaryl aldehyde oxime derivatives

A dramatic substituent effect was found in the silver(I)-catalyzed cyclization reaction of ortho-alkynylaryl aldehyde oxime derivatives. When R is an alkyl group, the Ag(I)-catalyzed reaction in dimethylacetamide at 110°C (conditions A) affords isoquinoli

Biphenylmethyl-substituted pyridones

Biphenylmethyl-substituted pyridones are prepared by reaction of pyridones with appropriate biphenylmethyl compounds. The biphenylmethyl-substituted pyridones can be employed as active compounds in medicaments, in particular for the treatment of arter