1101850-30-9

Basic information

• Product Name: (S)-N-{(R)-2-[bis(p-chlorophenyl)methylamino]-2-phenylethyl}prolinol
• Synonyms: (S)-N-{(R)-2-[bis(p-chlorophenyl)methylamino]-2-phenylethyl}prolinol
• CAS NO: 1101850-30-9
• Molecular Weight: 455.427
• Mol File: 1101850-30-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-N-{(R)-2-[bis(p-chlorophenyl)methylamino]-2-phenylethyl}prolinol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-{(R)-2-[bis(p-chlorophenyl)methylamino]-2-phenylethyl}prolinol(1101850-30-9)
• EPA Substance Registry System: (S)-N-{(R)-2-[bis(p-chlorophenyl)methylamino]-2-phenylethyl}prolinol(1101850-30-9)

Safety Data

• Hazardous Substances Data: 1101850-30-9(Hazardous Substances Data)

Upstream product

• 14212-38-5 bis(4-chlorophenyl)methanamine 
• 620179-31-9 N-(α-bromo-α-phenylacetyl)-(S)-proline methyl ester 

Relevant articles and documents

Kinetic resolution of β-alkenyl-, β-alkynyl- and β-flavenyl-substituted β-hydroxy esters in asymmetric dehydration

Catalytic asymmetric dehydration of β-alkenyl- or alkynyl-substituted β-hydroxy esters by kinetic resolution has been investigated with five different chiral ligands 3-7. The kinetic resolution of a variety of racemic β-hydroxy tert-butyl esters in the presence of a prolinol chiral ligand and BrZnCH2CO2tBu provided highly enantio-enriched β-hydroxy esters 9-22 with selectivity factors ranging from 11 to 59. In addition, the application of this asymmetric synthetic methodology to the preparation of enantio-enriched flavene derivatives 23-29 is demonstrated. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.