110247-81-9

Basic information

• Product Name: 1,1-diphenyl-2-o-tolylethane-1,2-diol
• Synonyms: 1,1-diphenyl-2-o-tolylethane-1,2-diol
• CAS NO: 110247-81-9
• Molecular Weight: 304.389
• Mol File: 110247-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-diphenyl-2-o-tolylethane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-diphenyl-2-o-tolylethane-1,2-diol(110247-81-9)
• EPA Substance Registry System: 1,1-diphenyl-2-o-tolylethane-1,2-diol(110247-81-9)

Safety Data

• Hazardous Substances Data: 110247-81-9(Hazardous Substances Data)

Upstream product

• 134-81-6 benzil 
• 25187-00-2 2-iodobenzophenone 
• 119-61-9 benzophenone 
• 529-20-4 2-methylphenyl aldehyde 
• 52056-22-1 2-hydroxy-1,2-diphenyl-2-o-tolyl-ethanone 
• 16216-14-1 o-methylbenzil 
• 932-31-0 ortho-tolylmagnesium bromide 
• 102477-86-1 2-hydroxy-2,2-diphenyl-1-o-tolyl-ethanone 

Downstream Products

• 111438-41-6 2,2-diphenyl-1-o-tolyl-ethanone 
• 102477-86-1 2-hydroxy-2,2-diphenyl-1-o-tolyl-ethanone 
• 111438-40-5 diphenyl-o-tolyl-acetaldehyde 

Relevant articles and documents

Reductive coupling between aromatic aldehydes and ketones or imines by copper catalysis

The copper-catalyzed reductive coupling of two different carbonyl compounds has been achieved. The reaction of aromatic aldehydes and arylketones with a silylboronate in the presence of a catalytic amount of a CuCl-N-heterocyclic carbene (NHC) complex and a stoichiometric amount of alkoxide base yielded cross-coupled 1,2-diol derivatives. A reaction pathway is proposed that involves the catalytic formation of a nucleophilic α-silyloxybenzylcopper(I) species from the aromatic aldehyde and its subsequent coupling with the arylketone. This process was amenable to asymmetric catalysis. This copper catalyst system also enabled the reductive coupling between aromatic aldehydes and imines.