110286-57-2Relevant articles and documents
Antibacterial compounds
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Page/Page column 18, (2008/06/13)
Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the
Antibacterial compounds
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Page/Page column 15, (2008/06/13)
Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, salts of prodrugs, and metabolites thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods
Novel inhibitors of bacterial protein synthesis: Structure-activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants
Clark, Richard F.,Wang, Sanyi,Ma, Zhenkun,Weitzberg, Moshe,Motter, Christopher,Tufano, Michael,Wagner, Rolf,Gu, Yu-Gui,Dandliker, Peter J.,Lerner, Claude G.,Chovan, Linda E.,Cai, Yingna,Black-Schaefer, Candace L.,Lynch, Linda,Kalvin, Douglas,Nilius, Angela M.,Pratt, Steve D.,Soni, Niru,Zhang, Tianyuan,Zhang, Xiaolin,Beutel, Bruce A.
, p. 3299 - 3302 (2007/10/03)
Structure-activity relationships for a recently discovered novel ribosome inhibitor (NRI) class of antibacterials were investigated. Preliminary efforts to optimize protein synthesis inhibitory activity of the series through modification of positions 3 an