110286-39-0

Basic information

• Product Name: (Z)-2-(2,6-Dichloro-5-fluoro-pyridine-3-carbonyl)-3-(2,4-dimethoxy-benzylamino)-acrylic acid ethyl ester
• Synonyms: (Z)-2-(2,6-Dichloro-5-fluoro-pyridine-3-carbonyl)-3-(2,4-dimethoxy-benzylamino)-acrylic acid ethyl ester
• CAS NO: 110286-39-0
• Molecular Weight: 457.286
• Mol File: 110286-39-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-2-(2,6-Dichloro-5-fluoro-pyridine-3-carbonyl)-3-(2,4-dimethoxy-benzylamino)-acrylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(2,6-Dichloro-5-fluoro-pyridine-3-carbonyl)-3-(2,4-dimethoxy-benzylamino)-acrylic acid ethyl ester(110286-39-0)
• EPA Substance Registry System: (Z)-2-(2,6-Dichloro-5-fluoro-pyridine-3-carbonyl)-3-(2,4-dimethoxy-benzylamino)-acrylic acid ethyl ester(110286-39-0)

Safety Data

• Hazardous Substances Data: 110286-39-0(Hazardous Substances Data)

Upstream product

• 96568-04-6 ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxopropanoate 
• 20781-20-8 2,4-Dimethoxybenzylamine 
• 96568-05-7 2,6-dichloro-α-(ethoxymethylene)-5-fluoro-β-oxo-3-pyridinepropanoic acid ethyl ester 

Downstream Products

• 110286-57-2 7-chloro-1-(2,4-dimethoxybenzyl)-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 635309-38-5 1-(2,4-dimethoxybenzyl)-6-fluoro-4-oxo-7-(pyrrolidin-1-yl)-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 779343-25-8 1-(2,4-dimethoxy-benzyl)-6-fluoro-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one 
• 779341-05-8 1-(2,4-dimethoxy-benzyl)-6-fluoro-4-oxo-7-pyrrolidin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carbaldehyde 
• 779343-11-2 1-(2,4-dimethoxy-benzyl)-6-fluoro-3-hydroxymethyl-7-pyrrolidin-1-yl-1H-[1,8]naphthyridin-4-one 
• 779337-66-5 1-(2,4-dimethoxybenzyl)-6-fluoro-4-oxo-7-pyrrolidin-1-yl-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid 

Relevant articles and documents

Novel inhibitors of bacterial protein synthesis: Structure-activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants

Structure-activity relationships for a recently discovered novel ribosome inhibitor (NRI) class of antibacterials were investigated. Preliminary efforts to optimize protein synthesis inhibitory activity of the series through modification of positions 3 an