635309-38-5Relevant articles and documents
Novel antibacterial class: A series of tetracyclic derivatives
Hinman, Mira M.,Rosenberg, Teresa A.,Balli, Darlene,Black-Schaefer, Candace,Chovan, Linda E.,Kalvin, Douglas,Merta, Philip J.,Nilius, Angela M.,Pratt, Steve D.,Soni, Niru B.,Wagenaar, Frank L.,Weitzberg, Moshe,Wagner, Rolf,Beutel, Bruce A.
, p. 4842 - 4856 (2007/10/03)
We describe the synthesis and antibacterial activity of a series of tetracyclic naphthyridones. The members of this series act primarily via inhibition of bacterial translation and belong to the class of novel ribosome inhibitors (NRIs). In this paper we
Rearrangements encountered in the attempted syntheses of pyridoazepinone carboxylic acids
Sanders, William J.,Zhang, Xiaolin,Wagner, Rolf
, p. 4527 - 4530 (2007/10/03)
(Chemical equation presented) Attempts to synthesize pyridoazepinone carboxylic acids such as 33 by standard methodologies resulted exclusively in unusual and unexpected rearrangement products. Seven-membered ring formation was attempted by ring expansion