110683-03-9Relevant articles and documents
A simple, general and efficient method for O and N-retinoylation. Application to the synthesis of 2-retinoyl-lecithin
Sangmam, Charles,Winum, Jean-Yves,Lucas, Marc,Montero, Jean-Louis,Chavis, Claude
, p. 2945 - 2958 (2007/10/03)
The synthesis of the new 1-stearoyl-2-retinoyl-glycero-3- phosphorylcholine by coupling of retinoic acid and lysolecithin with DCC- DMAP (1.2 eq.) is reported. This method is applied to O and N-retinoylation of uncharged organic substrates such as aliphatic alcohols, free hydroxyl anomeric sugars, aromatic amines and C-protected α-aminoacids.