110691-61-7

Basic information

• Product Name: (1R)-1,2,3,4-tetrahydro-6-hydroxy-7-methoxy-1-methoxycarbonyl-1-methyl-2-<<(R)-1-phenylethyl>carbamoyl>isoquinoline
• Synonyms: (1R)-1,2,3,4-tetrahydro-6-hydroxy-7-methoxy-1-methoxycarbonyl-1-methyl-2-<<(R)-1-phenylethyl>carbamoyl>isoquinoline
• CAS NO: 110691-61-7
• Molecular Weight: 398.459
• Mol File: 110691-61-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R)-1,2,3,4-tetrahydro-6-hydroxy-7-methoxy-1-methoxycarbonyl-1-methyl-2-<<(R)-1-phenylethyl>carbamoyl>isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-1,2,3,4-tetrahydro-6-hydroxy-7-methoxy-1-methoxycarbonyl-1-methyl-2-<<(R)-1-phenylethyl>carbamoyl>isoquinoline(110691-61-7)
• EPA Substance Registry System: (1R)-1,2,3,4-tetrahydro-6-hydroxy-7-methoxy-1-methoxycarbonyl-1-methyl-2-<<(R)-1-phenylethyl>carbamoyl>isoquinoline(110691-61-7)

Safety Data

• Hazardous Substances Data: 110691-61-7(Hazardous Substances Data)

Upstream product

• 645-33-0 3-hydroxy-4-methoxy-β-phenethylamine hydrochloride 
• 88598-26-9 salsoline-1-carboxylic acid 
• 33375-06-3 (1R)-1-phenylethyl isocyanate 
• 110691-59-3 Methyl(+/-)-Salsoline-1-methylcarboxylate 

Downstream Products

• 145122-35-6 (10bR)-6,10b-dihydro-8,9-dimethoxy-10b-methyl-2-<(R)-1-phenylethyl>-5H-imidazo<4,3-a>isoquinoline-1(2H),3(4H)-dione 

Relevant articles and documents

Enantioselective synthesis of 1-substituted tetrahydroisoquinoline-1-carboxylic acids

The 3,4-dihydroisoquinolinium salt 1 and its enantiomer have been converted readily and stereoselectively into (+)- and (-)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylisoquinoline-1-carboxylic acids.The synthetic route described should be applicable to the enantioselective synthesis of a variety of 1-alkyl- or 1-aryl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acids.The absolute configuration of the amino acid hydrochloride 11 was established to be as depicted in scheme 2.