88598-26-9 Usage
Chemical Class
Isoquinoline alkaloids
Derivative
Tetrahydroisoquinoline
Functional Group
Carboxylic acid
Potential Pharmacological Properties
Antioxidant and neuroprotective effects
Potential Use
Treatment of neurodegenerative diseases
Status
Potential lead compound for new drug development
Unique Features
Interesting structure and potential therapeutic applications for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 88598-26-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,5,9 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 88598-26:
(7*8)+(6*8)+(5*5)+(4*9)+(3*8)+(2*2)+(1*6)=199
199 % 10 = 9
So 88598-26-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO4/c1-16-10-6-8-7(5-9(10)14)3-4-13-11(8)12(15)17-2/h5-6,11,13-14H,3-4H2,1-2H3
88598-26-9Relevant articles and documents
Enantioselective synthesis of 1-substituted tetrahydroisoquinoline-1-carboxylic acids
Czarnocki, Zbigniew,Suh, Dennis,MacLean, David B.,Hultin, Philip G.,Szarek, Walter A.
, p. 1555 - 1561 (2007/10/02)
The 3,4-dihydroisoquinolinium salt 1 and its enantiomer have been converted readily and stereoselectively into (+)- and (-)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylisoquinoline-1-carboxylic acids.The synthetic route described should be applicable to the enantioselective synthesis of a variety of 1-alkyl- or 1-aryl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acids.The absolute configuration of the amino acid hydrochloride 11 was established to be as depicted in scheme 2.
