111623-28-0

Basic information

• Product Name: Phosphorane, triphenyl[(3,4,5-trimethoxyphenyl)methylene]-
• CAS NO: 111623-28-0
• Molecular Formula: C28H27O3P
• Molecular Weight: 442.494
• Mol File: 111623-28-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phosphorane, triphenyl[(3,4,5-trimethoxyphenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphorane, triphenyl[(3,4,5-trimethoxyphenyl)methylene]-(111623-28-0)
• EPA Substance Registry System: Phosphorane, triphenyl[(3,4,5-trimethoxyphenyl)methylene]-(111623-28-0)

Safety Data

• Hazardous Substances Data: 111623-28-0(Hazardous Substances Data)

Upstream product

• 21852-50-6 3,4,5-trimethoxybenzyl bromide 
• 603-35-0 triphenylphosphine 
• 61240-20-8 triphenyl-(3,4,5-trimethoxybenzyl)phosphonium bromide 

Downstream Products

• 1015697-68-3 (Z)-5-(4-ethoxy-3-nitrostyryl)-1,2,3-trimethoxybenzene 
• 1015697-67-2 C₃₈H₃₆O₅ 
• 61240-21-9 3,3′,4,4′,5,5′-hexamethoxy-(Z)-stilbene 
• 61240-22-0 dehydrobrittonin A 
• 134029-62-2 (E)-3,4,4',5-tetramethoxystilbene 
• 134029-49-5 3,4,5,4'-tetramethoxy-cis-stilbene 
• 15332-24-8 3,3',4,4',5,5'-hexamethoxystilbene 
• 1415089-13-2 (Z)-2-(2-(3,4,5-trimethoxyphenyl)vinyl)benzo[b]thiophene 
• 1415089-14-3 (E)-2-(2-(3,4,5-trimethoxyphenyl)vinyl)benzo[b]thiophene 
• 1124219-04-0 (Z)-2-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-benzofuran 
• 1415089-12-1 (E)-2-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-benzofuran 
• 121042-95-3 (Z)-5-(3-tert-butyldimethylsilyloxy-4-methoxystyryl)-1,2,3-trimethoxybenzene 

Relevant articles and documents

Antioxidant activity and inhibition of α-glucosidase by hydroxyl-functionalized 2-arylbenzo[b]furans

This study synthesized a series of hydroxyl-functionalized 2-arylbenzo[b]furans based on the structure of tournefolic acid A and evaluated them for antioxidant and a-glucosidase inhibitory activities. Compounds 5a, 5e, and 5n showed remarkable inhibition

THE PREPARTION AND THE USE OF ETHOXY COMBRETASTATINS AND THEIR PRODRUGS

The invention disclosed a total synthesis process of novel ethoxy combretastatins and their prodrugs. Combretastatins are chemically modified by ethoxy substituted on the 4'-position of their B aryl ring and are converted to be their soluble prodrugs of phosphate or their inner salt of phosphorylcholine by modifying the hydroxyl on the 3'-position of their B aryl ring. Similarly, 3'-amino combretastatin is 4'-ethoxy chemically modified and further side chain of amino acid can be introduced to the amino to form soluble prodrug of amino acidamide. The structure of the said compound is showed as formula (I). Ethoxy combretastatins possess potent tubulin polymerization inhibitory activity and can be used for the treatment of inhibiting tumor or neovascular.