15332-24-8

Basic information

• Product Name: Benzene, 1,1'-(1,2-ethenediyl)bis[3,4,5-trimethoxy-
• CAS NO: 15332-24-8
• Molecular Formula: C20H24O6
• Molecular Weight: 360.407
• Mol File: 15332-24-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(1,2-ethenediyl)bis[3,4,5-trimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(1,2-ethenediyl)bis[3,4,5-trimethoxy-(15332-24-8)
• EPA Substance Registry System: Benzene, 1,1'-(1,2-ethenediyl)bis[3,4,5-trimethoxy-(15332-24-8)

Safety Data

• Hazardous Substances Data: 15332-24-8(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 134029-74-6 [(3,4,5-trimethoxyphenyl)methyl]phosphoric acid diethyl ester 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 1916-07-0 3,4,5-trimethoxybenzoic acid methyl ester 
• 118-41-2 Eudesmic acid 
• 111623-28-0 C₂₈H₂₇O₃P 
• 634-36-6 1,2,3-trimethoxybenzene 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 621-62-5 chloroacetaldehyde diethyl acetal 
• 7251-01-6 3,4,5-trimethoxybenzaldehyde N-[-(3,4,5-trimethoxyphenyl)methylidene]hydrazone 

Downstream Products

• 61240-22-0 dehydrobrittonin A 
• 33284-74-1 brittonin A 

Relevant articles and documents

Activity of resveratrol triesters against primary acute lymphoblastic leukemia cells

Resveratrol is a common polyphenol of plant origin known for its cancer prevention and other properties. Its wider application is limited due to poor water solubility, low stability, and weak bioavailability. To overcome these limitations, a series of 13 novel resveratrol triesters were synthesized previously. In this paper, we describe the synthesis of 3 additional derivatives and the activity of all 16 against primary acute lymphoblastic leukemia cells. Of these, 3 compounds were more potent than resveratrol (IC50?=?10.5?μM) namely: resveratryl triacetate (IC50?=?3.4?μM), resveratryl triisobutyrate (IC50?=?5.1?μM), and resveratryl triisovalerate (IC50?=?4.9?μM); all other derivatives had IC50 values of >10?μM. Further studies indicated that the active compounds caused G1 phase arrest, increased expression of p53, and induced characteristics of apoptotic cell death. Moreover, the compounds were only effective in cycling cells, with cells arrested in G1 phase being refractory.