111865-51-1Relevant articles and documents
LiClO4-catalyzed three-component-coupling reactions: A facile synthesis of homoallylic amines
Yadav,Reddy,Reddy,Shesha Rao
, p. 6245 - 6247 (2002)
Lithium perchlorate catalyzes efficiently the three-component condensation of aldehydes, amines and allyltributylstannane under mild and neutral reaction conditions to afford the corresponding homoallylic amines in excellent yields.
Direct chemoselective allylation of inert amide carbonyls
Oda, Yukiko,Sato, Takaaki,Chida, Noritaka
, p. 950 - 953 (2012/04/18)
Direct allylation of inert amide carbonyls utilizing the Schwartz reagent afforded either substituted tertiary or secondary amines. A preactivation step was successfully avoided, which is generally a requisite to increase the electrophilicity of amides. The reaction exhibited remarkable functional group tolerance and proceeded even in the presence of methyl esters and nitro groups.
Synthetic and mechanistic studies of indium-mediated allylation of imines in ionic liquids
Man, Chun Law,Tin, Wai Cheung,Wong, Kwok-Yin,Tak, Hang Chan
, p. 923 - 929 (2007/10/03)
(Chemical Equation Presented) Aldimines derived from aryl and non-enolizable aliphatic aldehydes were allylated with allyl bromide mediated by indium powder in [bpy][BF4] (bpy = N-butylpyridine) to give good yields of the corresponding homoallylic amines. Selective formation of monoallylated amines can be achieved by varying the amount of bromide ion additive in the form of [bpy][Br]. The transient organoindium intermediates, allylindium-(I) and allylindium(III) dibromide formed in the reaction, were studied by NMR spectroscopy to explain the selectivity.