111869-44-4

Basic information

• Product Name: 7-(2,3-Didesoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-glycero-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on
• Synonyms: 7-(2,3-Didesoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-glycero-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on
• CAS NO: 111869-44-4
• Molecular Weight: 607.709
• Mol File: 111869-44-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-(2,3-Didesoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-glycero-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(2,3-Didesoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-glycero-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on(111869-44-4)
• EPA Substance Registry System: 7-(2,3-Didesoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-glycero-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on(111869-44-4)

Safety Data

• Hazardous Substances Data: 111869-44-4(Hazardous Substances Data)

Upstream product

• 111869-42-2 7-<2-Desoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-erythro-pentofuranosyl>-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on 
• 111902-68-2 7-(2-Desoxy-β-D-erythro-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on 
• 86392-75-8 7-deaza-2'-deoxyguanosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 111869-43-3 7-<2-Desoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-3-O-(phenoxythiocarbonyl)-β-D-erythro-pentofuranosyl>-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on 

Downstream Products

• 111869-49-9 2-amino-7-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin-4(3H)-one 

Relevant articles and documents

Synthesis of 7-Deaza-2',3'-dideoxyguanosine by Deoxygenation of Its 2'-Deoxy-β-D-ribofuranoside

7-Deaza-2',3'-dideoxyguanosine (4) was prepared by Barton deoxygenation from 7-deaza-2'-deoxyguanosine (1).Protection of the 5'-hydroxy group was accomplished by the 4,4'-dimethoxytriphenylmethyl residue.The 2-amino function was protected either with the same group or the dimethylaminomethylene residue.Assignment of 1H- and 13C-NMR signals of the 2',3'-dideoxy-β-D-glycero-pentofuranosyl moiety of 4 was made on the basis of 2D-NMR spectra.In contrast to 2',3'-dideoxyguanosine compound 4 has an extremely stable N-glycosylic bond towards proton-catalyzed hydrolysis.