112246-73-8 Usage
Description
(+)-Diisopinocampheyl chloroborane, commonly referred to as (+)-DIP-chloride, is a white to light yellow crystalline powder with unique chemical properties. It is a valuable reagent in the field of organic chemistry, particularly for its role in asymmetric reduction reactions.
Uses
Used in Pharmaceutical Industry:
(+)-Diisopinocampheyl chloroborane is used as a reagent for the asymmetric reduction of prochiral ketones, which is crucial for the synthesis of various pharmaceutical compounds. This application is significant because it allows for the selective production of specific enantiomers, which can have different biological activities and reduce potential side effects.
Used in Chemical Synthesis:
(+)-Diisopinocampheyl chloroborane is also used for the preparation of β-amino alcohols, which are important building blocks in the synthesis of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and natural products. The ability to produce these compounds with high enantioselectivity using (+)-DIP-chloride makes it a valuable tool in the development of new and improved chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 112246-73-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,2,4 and 6 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 112246-73:
(8*1)+(7*1)+(6*2)+(5*2)+(4*4)+(3*6)+(2*7)+(1*3)=88
88 % 10 = 8
So 112246-73-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H34BCl/c1-11-15-7-13(19(15,3)4)9-17(11)21(22)18-10-14-8-16(12(18)2)20(14,5)6/h11-18H,7-10H2,1-6H3/t11-,12+,13+,14-,15-,16+,17-,18+
112246-73-8Relevant articles and documents
AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
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Paragraph 1548, (2016/08/07)
Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
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Page/Page column 97, (2010/04/30)
Provided are sulphur-linked compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.