112375-54-9

Basic information

• Product Name: methyl (6E)-8-methylnon-6-enoate
• CAS NO: 112375-54-9
• Molecular Formula: C₁₁H₂₀O₂
• Molecular Weight: 184.2753
• Mol File: 112375-54-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 228.2°C at 760 mmHg
• Flash Point: 77°C
• Density: 0.887g/cm³
• Vapor Pressure: 0.0744mmHg at 25°C
• Refractive Index: 1.44
• CAS DataBase Reference: methyl (6E)-8-methylnon-6-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (6E)-8-methylnon-6-enoate(112375-54-9)
• EPA Substance Registry System: methyl (6E)-8-methylnon-6-enoate(112375-54-9)

Safety Data

• Hazardous Substances Data: 112375-54-9(Hazardous Substances Data)

Upstream product

• 179617-42-6 2-((E)-6-Methyl-hept-4-enyl)-malonic acid dimethyl ester 
• 59721-82-3 (E)-1-hydroxy-6-methylhept-4-ene 
• 179617-41-5 Methanesulfonic acid (E)-6-methyl-hept-4-enyl ester 
• 179617-47-1 trans-6-methyl-hept-4-enoic acid ethyl ester 
• 502-44-3 hexahydro-2H-oxepin-2-one 
• 6654-36-0 methyl 6-oxohexanoate 
• 4547-43-7 methyl 6-hydroxycaproate 
• 67-56-1 methanol 
• 404-86-4 capsaicin 

Downstream Products

• 59320-77-3 trans-8-methyl-6-nonenoic acid 
• 404-86-4 capsaicin 
• 95636-02-5 (E)-8-Methylnon-6-enoic acid chloride 
• 58493-48-4 trans-9-methyl-N-vanillyl-7-decenamide 
• 71226-60-3 Bishomocapsaicin 
• 19408-84-5 dihydrocapsaicin 
• 205687-01-0 capsiate 
• 946572-73-2 coniferyl (E)-8-methyl-6-nonenoate 

Relevant articles and documents

Isolation of coniferyl esters from Capsicum baccatum L., and their enzymatic preparation and agonist activity for TRPV1

Coniferyl esters-capsiconiate and dihydrocapsiconiate-were isolated from the fruits of the pepper, Capsicum baccatum L. var. praetermissum. Their structures were determined by spectroscopic methods to be coniferyl (E)-8-methyl-6-nonenoate (capsiconiate) a

A general and stereoselective synthesis of the capsaicinoids via the orthoester Claisen rearrangement

Capsaicin, a main pungent principle of hot pepper, and its 15 analogs have been efficiently synthesized. The key step of this synthetic scheme is the orthoester Claisen rearrangement, which transformed allylic alcohols 2A-C to (E)-alkenoates 3A-C (E/Z > 100) in a highly stereoselective manner. The subsequent carbon chain elongations on 3 based on the cyanation or the malonic acid ester synthesis afforded (E)-alkenoic acids 8, which were converted to the corresponding acid chloride and then coupled with vanillylamine to give capsaicinoids. HPLC and CE (capillary electrophoresis) analyses of these capsaicinoids were also carried out.