112474-32-5

Basic information

• Product Name: 2-Oxazolidinone, 5-methylene-3-phenyl-
• CAS NO: 112474-32-5
• Molecular Formula: C10H9NO2
• Molecular Weight: 175.187
• Mol File: 112474-32-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 5-methylene-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 5-methylene-3-phenyl-(112474-32-5)
• EPA Substance Registry System: 2-Oxazolidinone, 5-methylene-3-phenyl-(112474-32-5)

Safety Data

• Hazardous Substances Data: 112474-32-5(Hazardous Substances Data)

Upstream product

• 15332-75-9 (2-bromo-allyl)-phenyl-amine 
• 298-14-6 potassium hydrogencarbonate 
• 185384-36-5 N-(tert-butoxycarbonyl)-N-(prop-2-ynyl)aniline 
• 2651-82-3 phenyl-carbamic acid-(β,β'-dichloro-isopropyl ester) 
• 14465-74-8 N-phenyl-N-prop-2-ynylamine 
• 124-38-9 carbon dioxide 

Downstream Products

• 16938-99-1 <(carbomethoxy)phenylamino>acetone 

Relevant articles and documents

Copper-catalyzed cascade reactions of N-(2-bromoallyl)amines with KHCO 3 as the C1 source: An efficient process for the synthesis of oxazolidin-2-ones

A novel synthesis of oxazolidin-2-ones by carbamic acid formation and a subsequent copper-catalyzed intramolecular vinylation from N-(2-bromoallyl) amines and KHCO3 was developed. KHCO3 was used as a C1 source and base in this effici

In Situ Generated Zinc(II) Catalyst for Incorporation of CO2 into 2-Oxazolidinones with Propargylic Amines at Atmospheric Pressure

Incorporation of CO2 into heterocyclic compounds (i.e., 2-oxazolidinones) under mild conditions, especially at atmospheric pressure still remains challenging. The mononuclear ZnII complex ZnCl2(TBD)2, where TBD=

Non-Noble-Metal Metal-Organic-Framework-Catalyzed Carboxylative Cyclization of Propargylic Amines with Atmospheric Carbon Dioxide under Ambient Conditions

The coupling reaction of propargylic amines and carbon dioxide (CO2) to synthesize 2-oxazolidinones is an important reaction in industrial production, and yet harsh reaction conditions and noble-metal catalysts are often required to achieve high product yields. Herein, one novel noble-metal-free three-dimensional framework, [Mg3Cu2I2(IN)4(HCOO)2(DEF)4]n (1), assembled by magnesium and copper clusters was synthesized and applied to this reaction. Compound 1 displays excellent solvent stability. Importantly, 1, acting as heterogeneous catalyst, can highly catalyze the cyclization of propargylic amines with CO2 under atmospheric pressure at room temperature, which can be recycled at least five times without an obvious decrease of the catalytic activity. NMR spectroscopy, coupled with 13C-isotope- and deuterium-labeling experiments, clearly clarifies the mechanism of this catalytic system: CO2 was successfully captured and converted to the product of 2-oxazolidinones, the CC bond of propargylic amines can be effectively activated by 1, and proton transfer was involved in the reaction process. Density functional theory calculations are further conducted to uncover the reaction path and the crucial role of compound 1 during the reaction.