112561-97-4

Basic information

• Product Name: 3-Thiazolidinecarbothioamide, 2-(4-chlorophenyl)-N-methyl-
• CAS NO: 112561-97-4
• Molecular Formula: C11H13ClN2S2
• Molecular Weight: 272.823
• Mol File: 112561-97-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Thiazolidinecarbothioamide, 2-(4-chlorophenyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiazolidinecarbothioamide, 2-(4-chlorophenyl)-N-methyl-(112561-97-4)
• EPA Substance Registry System: 3-Thiazolidinecarbothioamide, 2-(4-chlorophenyl)-N-methyl-(112561-97-4)

Safety Data

• Hazardous Substances Data: 112561-97-4(Hazardous Substances Data)

Upstream product

• 7738-99-0 2-(4-chloro-phenyl)-thiazolidine 
• 556-61-6 methyl thioisocyanate 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones as hypoglycemic agents

A series of substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones was synthesized from amino alcohols or amino thiols and keto acids. A pharmacological model based on the results obtained with these compounds led to the synthesis and evaluation of a series of isoxazoles and other monocyclic compounds. These were evaluated for their ability to enhance glucose utilization in cultured L6 myocytes. The in vivo hypoglycemic efficacy and potency of these compounds were evaluated in a model of type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus), the ob/ob mouse. 25a(2S) (SDZ PGU 693) was selected for further pharmacological studies.