7738-99-0

Basic information

• Product Name: 2-(4-chlorophenyl)thiazolidine
• Synonyms: 3-Fluoro-2-hydroxybenzeneboronic acid pinacol ester
• CAS NO: 7738-99-0
• Molecular Formula: C₉H₁₀ClNS
• Molecular Weight: 199.7
• Mol File: 7738-99-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 330.4°Cat760mmHg
• Flash Point: 153.6°C
• Appearance: /Solid
• Density: 1.245g/cm³
• Vapor Pressure: 0.000167mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: 2-(4-chlorophenyl)thiazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)thiazolidine(7738-99-0)
• EPA Substance Registry System: 2-(4-chlorophenyl)thiazolidine(7738-99-0)

Safety Data

• Hazardous Substances Data: 7738-99-0(Hazardous Substances Data)

Usage

General Description

2-(4-chlorophenyl)thiazolidine is a chemical compound that belongs to the thiazolidine class. It is commonly used in the synthesis of pharmaceutical drugs and other organic compounds due to its versatile reactivity. The 4-chlorophenyl group attached to the thiazolidine ring adds additional chemical properties to the compound, making it a valuable building block in organic chemistry. Its unique structure and reactivity make it a valuable tool for researchers and chemists in the development of new drugs and materials.

InChI:InChI=1/C9H10ClNS/c10-8-3-1-7(2-4-8)9-11-5-6-12-9/h1-4,9,11H,5-6H2

Upstream product

• 156-57-0 2-mercaptoethylamine hydrochloride 
• 104-88-1 4-chlorobenzaldehyde 
• 60-23-1 Cysteamine 

Downstream Products

• 67189-33-7 2-(4-chloro-phenyl)-2,3-dimethyl-thiazolidine 
• 67224-60-6 2-(4-chloro-phenyl)-3-methyl-thiazolidine 
• 112561-97-4 2-(4-Chloro-phenyl)-thiazolidine-3-carbothioic acid methylamide 

Relevant articles and documents

Substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones as hypoglycemic agents

A series of substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones was synthesized from amino alcohols or amino thiols and keto acids. A pharmacological model based on the results obtained with these compounds led to the synthesis and evaluation of a series of isoxazoles and other monocyclic compounds. These were evaluated for their ability to enhance glucose utilization in cultured L6 myocytes. The in vivo hypoglycemic efficacy and potency of these compounds were evaluated in a model of type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus), the ob/ob mouse. 25a(2S) (SDZ PGU 693) was selected for further pharmacological studies.

Comparative radioprotective activity of various pentagonal compounds with two heteroatomes

Various heterocyclic compounds with two heteroatomes were synthesized and their potential radioprotective activity was tested. This study shows the interest of phenylthiazolidines derivatives in chemical radioprotection.